{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T01:47:31Z","timestamp":1763603251463,"version":"3.45.0"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T00:00:00Z","timestamp":1751846400000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Delayed hemolytic transfusion reaction (DHTR) is a rare post\u2010transfusion complication, typically involving extravascular hemolysis. We present an unusual case of postpartum DHTR caused by anti\u2010C antibodies in a 35\u2010year\u2010old Japanese woman, gravida 2, para 1, with no history of transfusion, alloimmunization, or underlying hemoglobinopathy. The patient developed dark\u2010colored urine on postpartum day 25, 12\u2009days after receiving a blood transfusion for hemorrhage due to placenta accreta spectrum. Laboratory findings revealed indirect hyperbilirubinemia, elevated lactate dehydrogenase, low haptoglobin, and hemoglobinuria, indicating concurrent extravascular and intravascular hemolysis. DHTR was confirmed by the detection of anti\u2010C antibodies and the presence of C\u2010antigen\u2010positive transfused red cells. Maternal sensitization likely resulted from subclinical fetomaternal transfusion, with an immune response triggered post\u2010transfusion. This case highlights the diagnostic challenges of DHTR in the postpartum setting, emphasizing the importance of post\u2010transfusion antibody screening and the need for heightened awareness of unexplained fever as a potential early indicator.<\/jats:p>","DOI":"10.1111\/jog.16362","type":"journal-article","created":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T22:13:11Z","timestamp":1751926391000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Uncommon postpartum delayed hemolytic transfusion reaction caused by anti\u2010C antibodies: A rare presentation without prior risk factors"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5015-5894","authenticated-orcid":false,"given":"Takehiko","family":"Mitsuyama","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology National Hospital Organization Kokura Medical Center  Kitakyushu 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