{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T01:42:38Z","timestamp":1763602958298,"version":"3.45.0"},"reference-count":18,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We report a rare case involving a 22\u2010year\u2010old phenotypically female patient who presented to our care with primary amenorrhea and spontaneous breast development. Hormonal analysis indicated hypergonadotropic hypogonadism, and imaging revealed a hypoplastic uterus and calcified ovaries. Karyotyping was 46, XY and the presence of the\n                    <jats:italic>SRY<\/jats:italic>\n                    gene was confirmed. The patient underwent laparoscopic bilateral salpingo\u2010oophorectomy due to the high risk of malignancy development. Histopathological analysis revealed bilateral Sertoli cell tumors and a sex cord tumor with annular tubules in the right gonad. Next generation sequencing genetic testing identified a 1.24\u2009Mb deletion on chromosome 9p24.3, which included the DMRT1, DMRT2, and DMRT3 genes, as well as a partial deletion of KANK1. Hormonal replacement therapy was not initiated due to the potential risk of tumor recurrence, and follow\u2010up imaging was scheduled every 6\u2009months for the first 2\u2009years and then annually. No recurrence was observed at 24\u2009months.\n                  <\/jats:p>","DOI":"10.1111\/jog.70027","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T11:24:55Z","timestamp":1754047495000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sertoli cell tumor associated with ovarian sex cord tumor with annular tubules in a patient with 46\n                    <scp>XY<\/scp>\n                    disorder of sex development and 9p24.3 deletion, case report"],"prefix":"10.1111","volume":"51","author":[{"given":"Tabatha","family":"Petrillo","sequence":"first","affiliation":[{"name":"Division of Obstetrics and Gynaecology AUSL of Modena  Carpi Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1563-7598","authenticated-orcid":false,"given":"Christian","family":"Battipaglia","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences for Mother, Child and Adult University of Modena and Reggio Emilia, Azienda Ospedaliero Universitaria Policlinico  Modena Italy"},{"name":"Clinical and Experimental Medicine PhD Programme, Department of Biomedical, Metabolic and Neural Sciences University of Modena and Reggio Emilia  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Semprini","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences for Mother, Child and Adult University of Modena and Reggio Emilia, Azienda Ospedaliero Universitaria Policlinico  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cinzia","family":"Baldessari","sequence":"additional","affiliation":[{"name":"Department of Oncology and Hematology Azienda Ospedaliero\u2010Universitaria Policlinico  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Pirola","sequence":"additional","affiliation":[{"name":"Department of Oncology and Hematology Azienda Ospedaliero\u2010Universitaria Policlinico  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Calabrese","sequence":"additional","affiliation":[{"name":"Medical Genetic Unit University Hospital of Modena  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonino","family":"Farulla","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences for Mother, Child and Adult University of Modena and Reggio Emilia, Azienda Ospedaliero Universitaria Policlinico  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giliana","family":"Ternelli","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences for Mother, Child and Adult University of Modena and Reggio Emilia, Azienda Ospedaliero Universitaria Policlinico  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albino","family":"Eccher","sequence":"additional","affiliation":[{"name":"Department of Pathology, Policlinico di Modena University of Modena and Reggio Emilia  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Botticelli","sequence":"additional","affiliation":[{"name":"Department of Pathology, Policlinico di Modena University of Modena and Reggio Emilia  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro D.","family":"Genazzani","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences for Mother, Child and Adult University of Modena and Reggio Emilia, Azienda Ospedaliero Universitaria Policlinico  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2019-00049"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MED.0000000000000113"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/omcr\/omaa024"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0738"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2019.04.018"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg.2017.60"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.5114\/pedm.2020.101803"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000293266"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.4158\/ep.9.3.220"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41431-024-01667-y"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdy001"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/106689690000800312"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.1998.13.1.89"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-022-02137-7"},{"issue":"3","key":"e_1_2_9_16_1","first-page":"257","article-title":"Bilateral dysgerminoma associated with gonadoblastoma and sex\u2010cord stromal tumour with annular tubules in a 28\u2010year\u2010old fertile woman with normal karyotype","volume":"44","author":"Young KMN","year":"2012","journal-title":"Pathology (Phila)"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19800501)45:9<2352::AID-CNCR2820450920>3.0.CO;2-#"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880079"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-015-1277-y"}],"container-title":["Journal of Obstetrics and Gynaecology 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