{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T06:06:26Z","timestamp":1764137186033,"version":"3.46.0"},"reference-count":14,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    A 25\u2010year\u2010old pregnant woman (gravida 2, para 1) presented with progressive anemia unresponsive to iron supplementation, ultimately developing pancytopenia at 37\u2009weeks of gestation. Despite adequate caloric intake, her diet consisted primarily of ultra\u2010processed and frozen foods. Laboratory findings showed hemoglobin of 5.5\u2009g\/dL, mean corpuscular volume of 102.9\u2009fL, and elevated lactate dehydrogenase. Her serum folate, vitamin B\n                    <jats:sub>12<\/jats:sub>\n                    , and zinc levels were 1.3\u2009ng\/mL, 131\u2009pg\/mL, and 57\u2009\u03bcg\/dL, respectively. A healthy infant was delivered via cesarean section at 38\u2009weeks, and the mother's pancytopenia improved with supplementation. To our knowledge, few reports have described concurrent folate\u2010 and zinc\u2010deficiency\u2013associated pancytopenia during pregnancy without significant weight loss or overt dietary restriction, particularly in the context of a diet high in ultra\u2010processed foods but with sufficient caloric intake. This case highlights the risks of poor micronutrient intake despite adequate macronutrient consumption and underscores the importance of nutritional monitoring during pregnancy.\n                  <\/jats:p>","DOI":"10.1111\/jog.70114","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:15:22Z","timestamp":1761783322000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pancytopenia in the Third Trimester of Pregnancy: A Case of Concurrent Folate and Zinc Deficiencies due to Unbalanced Dietary Habits"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-8141-3374","authenticated-orcid":false,"given":"Minori","family":"Tanabe","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Kurokawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kurume University School of Medicine  Kurume Japan"},{"name":"Department of Obstetrics and Gynecology National Organization Hospital Kyushu Medical Center  Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megumi","family":"Muto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maki","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology, Department of Medicine Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiyuki","family":"Yoshizato","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kurume University School of Medicine  Kurume Japan"},{"name":"Department of Obstetrics and Gynecology National Organization Hospital Kokura Medical Center  Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Nagafuji","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology, Department of Medicine Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naotake","family":"Tsuda","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu12020447"},{"volume-title":"Folic Acid Deficiency. StatPearls","year":"2025","author":"O'Leary F.","key":"e_1_2_11_3_1"},{"issue":"5","key":"e_1_2_11_4_1","article-title":"Zinc Deficiency and Associated Factors Among Pregnant Women Attending Antenatal Clinics in Public Health Facilities of Konso Zone, Southern Ethiopia","volume":"16","author":"Bitew Z. W.","year":"2021","journal-title":"PLoS One"},{"issue":"1","key":"e_1_2_11_5_1","first-page":"80","article-title":"Basic Study of Zn Measurement Using the Reagent \u2018Espa\u2010Zn II\u2019: Performance Evaluation of Zinc Measurement Reagent","volume":"70","author":"Tateishi W.","year":"2021","journal-title":"Igaku Kensa"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(86)90771-4"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(01)00465-1"},{"issue":"2","key":"e_1_2_11_8_1","first-page":"46","article-title":"Vitamin B12 Deficiency Presenting as Pancytopenia in Pregnancy: A Case Report","volume":"7","author":"Idris N.","year":"2012","journal-title":"Malaysian Family Physician"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2014-207861"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr\u20102022\u2010249955"},{"issue":"10","key":"e_1_2_11_11_1","first-page":"1756","article-title":"Ultra\u2010Processed Food Consumption Is Related to Higher Trans Fatty Acids, Sugar Intake, and Micronutrient\u2010Impaired Status in Schoolchildren of Bahia, Brazil","volume":"20","author":"Martins A. P. B.","year":"2017","journal-title":"Public Health Nutrition"},{"issue":"9","key":"e_1_2_11_12_1","first-page":"1555","article-title":"Intake of Ultra\u2010Processed Food, Dietary Diversity and the Risk of Nutritional Inadequacy Among Adults in India","volume":"23","author":"Chakrabarti R.","year":"2020","journal-title":"Public Health Nutrition"},{"issue":"3","key":"e_1_2_11_13_1","first-page":"699","article-title":"Ultra\u2010Processed Foods and Schooling Are Independently Associated With Lower Iron and Folate Consumption by Pregnant Women Followed in Primary Health Care","volume":"12","author":"Lima E. E. S.","year":"2020","journal-title":"Nutrients"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.14506"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.14770"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.70114","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T06:01:01Z","timestamp":1764136861000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.70114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,29]]},"references-count":14,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1111\/jog.70114"],"URL":"https:\/\/doi.org\/10.1111\/jog.70114","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"type":"print","value":"1341-8076"},{"type":"electronic","value":"1447-0756"}],"subject":[],"published":{"date-parts":[[2025,10,29]]},"assertion":[{"value":"2025-02-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70114"}}