{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T06:05:42Z","timestamp":1764137142548,"version":"3.46.0"},"reference-count":35,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T00:00:00Z","timestamp":1762128000000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study presents a case of vesicouterine fistula (VUF) diagnosed during pregnancy and offers a systematic review to identify clinical guidance for managing this rare but serious obstetric complication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a systematic review of international databases from inception to May 2025, including studies on VUF diagnosed during pregnancy regardless of obstetric outcome. Studies on other genitourinary fistulas, non\u2010pregnant women, or extrauterine pregnancies were excluded. No study design restrictions were applied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010two VUF cases with primary intrauterine implantation during pregnancy were identified, including one from our center. All had prior cesarean delivery (100%). Fourteen fetuses (63.6%) died, one pregnancy (4.5%) was terminated surgically, and seven (31.8%) resulted in live births. Conservative treatment included antibiotics and bladder catheterization. Among viable cases: two full\u2010term (9.1%), one preterm (32\u201334\u2009weeks, 4.5%), and four preterm (&lt;\u200932\u2009weeks, 18.2%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Available evidence on VUF during pregnancy consists solely of case reports. Gestational age and fetal viability are key factors in guiding treatment (expectant management versus intervention). This review underscores the risk of complications and highlights the need for careful evaluation in women with risk factors, especially those with urinary or menstrual symptoms following cesarean delivery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jog.70127","type":"journal-article","created":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T08:46:31Z","timestamp":1762159591000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Vesicouterine Fistula During Pregnancy: Case Report and Systematic Literature Review on Clinical Characteristics, Management, and Outcomes"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5885-0436","authenticated-orcid":false,"given":"Erica","family":"Trimarchi","sequence":"first","affiliation":[{"name":"Unit of Obstetrics and Gynecology, Department of Surgery, Dentistry, Pediatrics, and Gynecology University of Verona, Azienda Ospedaliera Universitaria Integrata Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Stringari","sequence":"additional","affiliation":[{"name":"Unit of Obstetrics and Gynecology, Department of Surgery, Dentistry, Pediatrics, and Gynecology University of Verona, Azienda Ospedaliera Universitaria Integrata Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippo","family":"Migliorini","sequence":"additional","affiliation":[{"name":"Department of Urology University of Verona, Azienda Ospedaliera Universitaria Integrata Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Festi","sequence":"additional","affiliation":[{"name":"Unit of Obstetrics and Gynecology, Department of Surgery, Dentistry, Pediatrics, and Gynecology University of Verona, Azienda Ospedaliera Universitaria Integrata Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pier Carlo","family":"Zorzato","sequence":"additional","affiliation":[{"name":"Unit of Obstetrics and Gynecology, Department of Surgery, Dentistry, Pediatrics, and Gynecology University of Verona, Azienda Ospedaliera Universitaria Integrata Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariachiara","family":"Bosco","sequence":"additional","affiliation":[{"name":"Unit of Obstetrics and Gynecology, Department of Surgery, Dentistry, Pediatrics, and Gynecology University of Verona, Azienda Ospedaliera Universitaria Integrata Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Garzon","sequence":"additional","affiliation":[{"name":"Unit of Obstetrics and Gynecology, Department of Surgery, Dentistry, Pediatrics, and Gynecology University of Verona, Azienda Ospedaliera Universitaria Integrata Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Antonelli","sequence":"additional","affiliation":[{"name":"Department of Urology University of Verona, Azienda Ospedaliera Universitaria Integrata Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Uccella","sequence":"additional","affiliation":[{"name":"Unit of Obstetrics and Gynecology, Department of Surgery, Dentistry, Pediatrics, and Gynecology University of Verona, Azienda Ospedaliera Universitaria Integrata Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,3]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2006.03591.x"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1023\/a:1024443822378"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1996.tb09522.x"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-1591.120123"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-7796.110014"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-022-05384-2"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2012.31.8.1294"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/21681805.2017.1418019"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)67597-9"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-017-4350-8"},{"key":"e_1_2_13_13_1","unstructured":"V.Lesovoy Y.Parashchuk D.Shchukin et\u00a0al. \u201cFetus in the Bladder: Rare Complication of Vesicouterine Fistula. 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