{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T06:05:27Z","timestamp":1764137127368,"version":"3.46.0"},"reference-count":46,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Postpartum hemorrhage (PPH) remains the most common cause of maternal death worldwide. Although obstetric bleeding often begins with structural causes such as uterine atony or tissue trauma, delayed hemostasis rapidly leads to consumption and dilution of coagulation factors, culminating in secondary coagulopathy. Effective prevention of maternal death therefore requires both rapid control of bleeding and timely correction of coagulation failure. Traditionally, plasma\u2010based laboratory assays such as PT, aPTT, and Clauss fibrinogen have served as the diagnostic standard. However, their prolonged turnaround time restricts real\u2010time applicability. Viscoelastic testing (TEG\/ROTEM) has expanded bedside coagulation assessment by visualizing clot formation and fibrinolysis, enabling goal\u2010directed transfusion therapy, yet still demands time and expertise. Recent advances in point\u2010of\u2010care (POC) fibrinogen measurement now permit rapid quantification directly from whole blood, producing results within 2\u2009min and allowing immediate, evidence\u2010based replacement decisions. Integrating these three modalities\u2014POC measurement of fibrinogen for rapid response, viscoelastic testing for dynamic evaluation, and laboratory testing for standardization\u2014constitutes an optimal, tiered framework for managing obstetric coagulopathy. This multimodal approach accelerates intervention, improves precision, and enhances safety in PPH management. Future directions include the broader dissemination of POC measurement devices, multicenter validation of clinical benefit, and development of digital decision\u2010support systems for real\u2010time coagulation monitoring. A structured, data\u2010driven coagulation strategy may finally render maternal death from PPH a fully preventable event.<\/jats:p>","DOI":"10.1111\/jog.70134","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T23:47:15Z","timestamp":1762904835000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Postpartum Hemorrhage: Preventable Maternal Deaths and the Role of Coagulation Monitoring"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6068-5345","authenticated-orcid":false,"given":"Hiroyuki","family":"Sumikura","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Critical Care Medicine Yokohama City University Medical Center  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,11]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214\u2010109X(14)70227\u2010X"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102393\u20109\u201055"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2021.102982"},{"issue":"6","key":"e_1_2_11_5_1","first-page":"875","article-title":"Prevention and Management of Postpartum Hemorrhage","volume":"75","author":"Anderson J. 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