{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T06:05:27Z","timestamp":1764137127106,"version":"3.46.0"},"reference-count":15,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Nonsteroidal anti\u2010inflammatory drugs (NSAIDs) are generally avoided in late pregnancy due to fetal risks, such as premature ductus arteriosus closure. However, celecoxib, a selective cyclooxygenase 2 (COX\u20102) inhibitor, may help manage pain and uterine contractions with fewer adverse effects. Here, we report a case of a 37\u2010year\u2010old primiparous woman with uterine adenomyosis who was treated with celecoxib and ritodrine hydrochloride for severe pain and threatened preterm labor in the second trimester. This combination effectively reduced symptoms, allowing prolongation of pregnancy. However, labor commenced shortly after discontinuation of celecoxib at 28\u2009weeks of gestation, requiring an emergency cesarean section. The neonate had no significant complications, and the patient's pain resolved postpartum. This case demonstrates that celecoxib can be a viable option for managing pain and contractions in pregnancy complicated by adenomyosis; however, further studies are needed to assess its long\u2010term safety.<\/jats:p>","DOI":"10.1111\/jog.70135","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T08:19:20Z","timestamp":1762849160000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prolonged Pregnancy Following Long\u2010Term Celecoxib Use in a Case of Uterine Adenomyosis: A Case Report"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-7237-0964","authenticated-orcid":false,"given":"Yuichiro","family":"Hirayama","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine Juntendo University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shun","family":"Masaoka","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine Juntendo University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6195-8971","authenticated-orcid":false,"given":"Jun","family":"Takeda","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine Juntendo University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuko","family":"Hirai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine Juntendo University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiguna","family":"Sei\u2010Okawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine Juntendo University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4554-164X","authenticated-orcid":false,"given":"Atsuo","family":"Itakura","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine Juntendo University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.j1909"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2020.11.013"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2018.12.006"},{"key":"e_1_2_10_5_1","unstructured":"Ministry of Health \u201cLabour and Welfare. Specified Report of Vital Statistics 2023. Vital Health and Social Statistics Office \u201d2023."},{"issue":"2","key":"e_1_2_10_6_1","first-page":"1","article-title":"Births: Final Data for 2022","volume":"73","author":"MJK O.","year":"2024","journal-title":"National Vital Statistics Reports"},{"key":"e_1_2_10_7_1","unstructured":"Eurostat \u201cFertility Indicators \u201d2024 https:\/\/ec.europa.eu\/eurostat\/en\/."},{"issue":"2","key":"e_1_2_10_8_1","first-page":"89","article-title":"Epidemiology of Adenomyosis","volume":"38","author":"Upson K.","year":"2020","journal-title":"Seminars in Reproductive Medicine"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2017.1285895"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjog.2022.02.015"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.125281"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/01443615.2011.618892"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1999.276.3.R913"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/869698"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000124784.48287.15"},{"issue":"4","key":"e_1_2_10_16_1","first-page":"567","article-title":"Efficacy and Safety of Indomethacin Versus Ritodrine in the Management of Preterm Labor: A Randomized Study","volume":"74","author":"Morales W. 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