{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T12:14:15Z","timestamp":1781093655319,"version":"3.54.1"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate fetal growth outcomes in gestational diabetes diagnosed before 20\u2009weeks' gestation (E\u2010GDM) following immediate intervention and to identify factors associated with abnormal fetal growth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed singleton term pregnancies with E\u2010GDM between 2016 and 2021 at two university hospitals in Japan: Keio University Hospital (KUH) and Yokohama City University Medical Center (YCUMC). Dietary management was initiated immediately after diagnosis in both hospitals. At KUH, all E\u2010GDM women underwent self\u2010monitoring of blood glucose (SMBG). At YCUMC, the indication for SMBG was determined based on pre\u2010pregnancy weight, the number of abnormal values on the oral glucose tolerance test, and other glycemic biomarkers, including HbA1c and glycated albumin. Fetal growth outcomes, assessed as the proportions of large\u2010for\u2010gestational\u2010age (LGA) and small\u2010for\u2010gestational\u2010age (SGA), were evaluated in E\u2010GDM receiving early management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 509 pregnancies (190 at KUH and 319 at YCUMC), LGA and SGA were observed in 63 (12%) and 46 (9%), respectively. The proportion of LGA was not significantly associated with pre\u2010pregnancy BMI (underweight, 9.6%; normal, 11%; overweight\/obese, 16%:\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.20). In contrast, there was a significant difference in the proportion of SGA among the three groups (underweight, 19%; normal, 8.2%; overweight\/obese, 7.2%:\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.024). Multivariate analysis demonstrated that pre\u2010pregnancy underweight was significantly associated with SGA in comparison with pre\u2010pregnancy normal weight.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Fetal growth outcomes in E\u2010GDM receiving early intervention were comparable to that of uncomplicated Japanese pregnancies. Since pre\u2010pregnancy underweight remained a risk factor of SGA, clinicians should pay attention to the development of SGA in lean women with E\u2010GDM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jog.70199","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T05:13:24Z","timestamp":1770873204000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Fetal Growth Outcomes in Early Gestational Diabetes Mellitus Managed Immediately After Diagnosis"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3694-4340","authenticated-orcid":false,"given":"Sayuri","family":"Nakanishi","sequence":"first","affiliation":[{"name":"Perinatal Center for Maternity and Neonate Yokohama City University Medical Center  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Miyakoshi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology International Catholic Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maki","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Ehime University Graduate School of Medicine  Toon Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshifumi","family":"Kasuga","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6808-0911","authenticated-orcid":false,"given":"Noriyuki","family":"Iwama","sequence":"additional","affiliation":[{"name":"Center for Maternal and Perinatal Medicine Tohoku University Hospital  Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology National Hospital Organization Nagasaki Medical Center  Omura Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeru","family":"Aoki","sequence":"additional","affiliation":[{"name":"Perinatal Center for Maternity and Neonate Yokohama City University Medical Center  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7129-9175","authenticated-orcid":false,"given":"Ichiro","family":"Yasuhi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology National Hospital Organization Nagasaki Medical Center  Omura Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Ehime University Graduate School of Medicine  Toon 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