{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T10:55:09Z","timestamp":1791975309318,"version":"4.4.0"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Uterine smooth muscle tumor of uncertain malignant potential (STUMP) is a rare \u201cgray\u2010zone\u201d entity characterized by unpredictable postoperative behavior and the absence of standardized surveillance strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe postoperative clinical course, recurrence patterns, and fertility\u2010related outcomes in patients with STUMP managed at a tertiary center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective observational study including 27 patients with a final pathology diagnosis of STUMP who underwent surgery and had postoperative follow\u2010up available between 2009 and 2025. Clinical, surgical, and pathological variables were collected from hospital records. Recurrence was defined as radiologic evidence of a new lesion during follow\u2010up and categorized by anatomic site. Outcomes included recurrence status, time to recurrence, recurrence histology, subsequent management, and pregnancy outcomes after uterus\u2010sparing surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Median follow\u2010up was 58 months (IQR 17\u201379; range 4\u2013136). Recurrence occurred in six patients (22.2%), with a median time to recurrence of 36 months (IQR 8\u201366.3). Recurrences were local (\n                      <jats:italic>n<\/jats:italic>\n                      =\u20094) or pulmonary (\n                      <jats:italic>n<\/jats:italic>\n                      =\u20092); one patient with lung recurrence also had wrist soft\u2010tissue involvement. Histology at recurrence included leiomyosarcoma (\n                      <jats:italic>n<\/jats:italic>\n                      =\u20092), STUMP (\n                      <jats:italic>n<\/jats:italic>\n                      =\u20092), and leiomyoma (\n                      <jats:italic>n<\/jats:italic>\n                      =\u20092). All recurrent cases underwent secondary surgery. One death occurred during follow\u2010up. Uterus\u2010sparing surgery was performed in nine patients (33.3%); recurrence occurred in four, all local. Two pregnancies were recorded, including one live birth.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>STUMP shows heterogeneous postoperative behavior, including late and occasionally malignant or distant recurrences. Long\u2010term surveillance is warranted, and uterus\u2010sparing management may be considered in carefully selected patients with fertility goals under close follow\u2010up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jog.70251","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T02:01:31Z","timestamp":1773972091000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Uterine Smooth Muscle Tumors of Uncertain Malignant Potential (\n                    <scp>STUMP<\/scp>\n                    ): Clinical Course and Follow\u2010Up Outcomes After Surgery"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4117-8118","authenticated-orcid":false,"given":"Arif Onur","family":"Atay","sequence":"first","affiliation":[{"name":"Obstetrics and Gynecology Department Torbal\u0131 State Hospital  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gurdeniz","family":"Serin","sequence":"additional","affiliation":[{"name":"Pathology Department Ege University Faculty of Medicine  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Akdemir","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Ege University Faculty of Medicine  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levent","family":"Akman","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Ege University Faculty of Medicine  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa Cosan","family":"Terek","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Ege University Faculty of Medicine  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osman","family":"Zekioglu","sequence":"additional","affiliation":[{"name":"Pathology Department Ege University Faculty of Medicine  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teksin","family":"Cirpan","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Ege University Faculty of Medicine  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.14064"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.31083\/j.ejgo.2020.06.2178"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2015.3"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjog.2022.08.003"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/pap.0b013e3181cfb901"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina59081371"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2019.30.e54"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.13515"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.31083\/j.ceog4912267"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2019.07.002"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2021.08.010"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181a02d1c"},{"issue":"11","key":"e_1_2_13_14_1","first-page":"8136","article-title":"Uterine Smooth Muscle Tumors of Uncertain Malignant Potential (STUMP): Pathology, Follow\u2010Up and Recurrence","volume":"7","author":"Dall'Asta A.","year":"2014","journal-title":"International Journal of Clinical and Experimental Pathology"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/hropen\/hoaf009"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc\u20102022\u2010004038"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000001178"}],"container-title":["Journal of Obstetrics and Gynaecology 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