{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T10:12:47Z","timestamp":1788862367226,"version":"build-2803163510"},"reference-count":48,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T00:00:00Z","timestamp":1778025600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the link between serum 25\u2010hydroxyvitamin D [25(OH)D] and obesity in postmenopausal women, and to evaluate the potential mediating effect of the atherogenic index of plasma (AIP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this cross\u2010sectional analysis, data from 3386 postmenopausal women were extracted from the National Health and Nutrition Examination Survey (2011\u20132018). Participants were stratified by vitamin D status: deficient (&lt;\u200950\u2009nmol\/L), insufficient (50\u201375\u2009nmol\/L), and sufficient (\u2265\u200975\u2009nmol\/L). Adjusted weighted regression models assessed associations with body mass index (BMI) and obesity (BMI \u2265\u200930\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ), while mediation analysis quantified the role of AIP.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After comprehensive covariate adjustment, a significant inverse relationship was observed between serum 25(OH)D and BMI (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22122.36, 95% CI: \u22123.16, \u22121.55). Vitamin D deficient women exhibited a mean BMI increase of 1.98\u2009units (95% CI: 0.96, 3.00) and an elevated odds of obesity (OR\u2009=\u20091.81, 95% CI: 1.30, 2.50) relative to the sufficient group. These findings were robust across demographic and clinical subgroups. Mediation analysis indicated AIP accounted for 9.53% of the association with BMI and 9.40% with obesity (both\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study demonstrates a significant inverse association between vitamin D status and obesity in postmenopausal women, with lipid metabolism, as reflected by AIP, partially mediating this relationship. Further longitudinal research is required to establish causality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jog.70325","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T01:42:29Z","timestamp":1778118149000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Vitamin D and Body Mass Index\/Obesity in Postmenopausal Women: A Cross\u2010Sectional Study With Analysis of the Atherogenic Index of Plasma as a Mediator"],"prefix":"10.1111","volume":"52","author":[{"given":"Xuanping","family":"Lu","sequence":"first","affiliation":[{"name":"Reproductive Medicine Center First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Zhou","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Center First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0418-1075","authenticated-orcid":false,"given":"Caiping","family":"Mao","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Center First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiqin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Center First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6028-9176","authenticated-orcid":false,"given":"Xiaoling","family":"Deng","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Center First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuqing","family":"Song","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Center First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,6]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.7570\/jomes20008"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14102049"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.110.010272"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.11.009"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ags3.12049"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2010.2"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.906895"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1984.64.2.478"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2019.06.010"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu10111656"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu7095383"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15132978"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu5030949"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12239"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2014.900004"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000008058"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/1765835"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10071700"},{"issue":"163","key":"e_1_2_12_20_1","first-page":"1","article-title":"National Health and Nutrition Examination Survey: National Youth Fitness Survey Plan, Operations, and Analysis, 2012","author":"Borrud L.","year":"2014","journal-title":"Vital and Health Statistics. 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