{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T10:12:47Z","timestamp":1788862367182,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To identify congenital pulmonary airway malformation (CPAM) volume ratio (CVR) values that can predict the need for early neonatal surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed 70 infants diagnosed with congenital cystic lung diseases (CCLD) over the past 10\u2009years at our center (10 with CPAM, 25 with intra\u2010 and extra\u2010lobar bronchopulmonary sequestrations, and 35 with bronchial atresia). Perinatal features, the maximum CVR during pregnancy, and the final CVR before delivery were compared between the early surgery group (surgery within 1\u2009week of birth) and the follow\u2010up group (surgery after 1\u2009week of birth or no surgery).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among all fetuses with CCLD, the median maximum and final CVR values were 1.2 (interquartile range [IQR]: 0.7\u20131.9) and 0.5 (IQR: 0.2\u20130.9) with a median gestational age of 26\u2009weeks (IQR: 24\u201330) and 34\u2009weeks (IQR: 32\u201337), respectively. Early neonatal surgery was required in nine infants (five with CPAM, one with bronchopulmonary sequestrations, and three with bronchial atresia). Compared to the follow\u2010up groups, patients in the early surgery group had higher maximum CVR, higher final CVR, and a greater incidence of polyhydramnios. The maximum and final CVR thresholds of 1.86 and 0.9, yielded sensitivity of 78% and 78% and specificity of 80% and 85%, respectively. The areas under the curve for the maximum and final CVR values were 0.85 and 0.88, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A maximum CVR threshold of 1.86 and a final CVR threshold of 0.9 may be useful indicators for predicting the need for early neonatal surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jog.70327","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T00:56:06Z","timestamp":1778806566000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Congenital Pulmonary Airway Malformation Volume Ratio in Fetuses With Congenital Cystic Lung Diseases to Predict Surgery Within 7\u2009Days of Birth"],"prefix":"10.1111","volume":"52","author":[{"given":"Fumi","family":"Yanagisawa","sequence":"first","affiliation":[{"name":"Division of Obstetrics and Gynecology Kanagawa Children's Medical Center  Yokohama Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4682-8667","authenticated-orcid":false,"given":"Yuki","family":"Kamihara","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynecology Kanagawa Children's Medical Center  Yokohama Kanagawa Japan"},{"name":"Perinatal Center for Maternity and Neonates Yokohama City University Medical Center  Yokohama City Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Shimokaze","sequence":"additional","affiliation":[{"name":"Division of Neonatology Kanagawa Children's Medical Center  Yokohama Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michi","family":"Kasai","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynecology Kanagawa Children's Medical Center  Yokohama Kanagawa 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