{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T06:01:28Z","timestamp":1784700088830,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Spondyloepiphyseal dysplasia congenita (SEDC) is a rare skeletal dysplasia caused by heterozygous pathogenic variants in\n                    <jats:italic>COL2A1<\/jats:italic>\n                    , with short\u2010trunk stature and respiratory compromise during pregnancy. We report a 30\u2010year\u2010old primigravida with SEDC who achieved full\u2010term delivery under multidisciplinary management. Fetal ultrasound findings suggested that the fetus also had SEDC. She was admitted at 33\u2009weeks for respiratory monitoring. At 34\u2009weeks, asymptomatic nocturnal SpO\n                    <jats:sub>2<\/jats:sub>\n                    desaturation to 91% was detected; pulmonary embolism and cardiac dysfunction were excluded. Low\u2010flow nocturnal oxygen supplementation (1\u2009L\/min) maintained SpO\n                    <jats:sub>2<\/jats:sub>\n                    above 96%. An elective cesarean section was performed at 37\u2009weeks for cephalopelvic disproportion, delivering a boy who required temporary ventilatory support and was diagnosed with SEDC through radiographic assessment. This case highlights the utility of maternal genetic diagnosis in anticipating fetal skeletal dysplasia and demonstrates that with careful respiratory surveillance and perinatal planning, expectant management to term is feasible even in cases of maternal SEDC.\n                  <\/jats:p>","DOI":"10.1111\/jog.70409","type":"journal-article","created":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T13:52:21Z","timestamp":1784123541000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Closely Monitored Successful Full\u2010Term Delivery in a Woman With Spondyloepiphyseal Dysplasia Congenita: A Case Report and Literature Review"],"prefix":"10.1111","volume":"52","author":[{"given":"Masako","family":"Ueki","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Shinshu University School of Medicine  Matsumoto Nagano Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4695-9017","authenticated-orcid":false,"given":"Motoki","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shinshu University School of Medicine  Matsumoto Nagano Japan"},{"name":"Department of Obstetrics, Gynecology and Reproductive Sciences Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0585-8131","authenticated-orcid":false,"given":"Motoko","family":"Kamiya","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Shinshu University School of Medicine  Matsumoto Nagano Japan"},{"name":"Center for Medical Genetics Shinshu University Hospital  Matsumoto Nagano Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Yokokawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shinshu University School of Medicine  Matsumoto Nagano Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shinshu University School of Medicine  Matsumoto Nagano Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4450-5142","authenticated-orcid":false,"given":"Ryoichi","family":"Asaka","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shinshu University School of Medicine  Matsumoto Nagano Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiho","family":"Fuseya","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shinshu University School of Medicine  Matsumoto Nagano Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0276-248X","authenticated-orcid":false,"given":"Norihiko","family":"Kikuchi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shinshu University School of Medicine  Matsumoto Nagano Japan"},{"name":"Department of Obstetrics and Gynecology Nagano Red Cross Hospital  Nagano Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanri","family":"Shiozawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shinshu University School of Medicine  Matsumoto Nagano Japan"},{"name":"Department of Obstetrics and Gynecology Aizawa Hospital  Matsumoto Nagano Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1513-9473","authenticated-orcid":false,"given":"Tsutomu","family":"Miyamoto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shinshu University School of Medicine  Matsumoto Nagano Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/TACG.S197205"},{"issue":"3","key":"e_1_2_11_3_1","first-page":"1024","article-title":"A Case of Mother and Fetus With Spondyloepiphyseal Dysplasia Congenita","volume":"49","author":"Iwata A.","year":"2013","journal-title":"Journal of Japan Society of Perinatal and Neonatal Medicine"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-14508-9"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ped.12331"},{"issue":"5","key":"e_1_2_11_6_1","first-page":"896","article-title":"Spondyloepiphyseal Dysplasia Congenita: Genetic Linkage to Type II Collagen (COL2AI)","volume":"46","author":"Anderson I. 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