{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:07:30Z","timestamp":1790125650154,"version":"4.0.1"},"reference-count":32,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To compare the burden, temporal trends, risk factor attribution, and future projections of cervical, uterine, and ovarian cancers among Chinese women aged 55\u2009years and older.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a population\u2010based descriptive and projection analysis using data from the Global Burden of Disease Study 2021. Incidence, mortality, disability\u2010adjusted life years (DALYs), and corresponding age\u2010standardized rates for cervical, uterine, and ovarian cancers were extracted for 1990\u20132021. Age\u2010specific burden, temporal trends, and attributable risk factors were examined. Incidence and mortality from 2022 to 2036 were projected using a Bayesian age\u2010specific trend model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From 1990 to 2021, the absolute numbers of incident cases, deaths, and DALYs increased for all three cancers among Chinese women aged 55\u2009years and older, whereas age\u2010standardized mortality and DALY rates generally declined. In 2021, cervical cancer showed the highest overall burden, with mortality rates increasing markedly in the oldest age groups. Uterine cancer showed the largest increase in incidence age\u2010standardized rate and a burden concentrated mainly in the younger segment of older women. Ovarian cancer showed a relatively unfavorable mortality pattern and was projected to have increasing incidence and mortality through 2036. Risk attribution differed by cancer type: cervical cancer mortality was mainly attributable to unsafe sex, uterine cancer mortality to high body mass index, and ovarian cancer mortality to mixed metabolic and environmental or occupational risks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Cervical, uterine, and ovarian cancers remain substantial and heterogeneous health burdens among older Chinese women. Despite declines in age\u2010standardized mortality and DALY rates, population aging is likely to increase the absolute burden. Age\u2010specific prevention, screening, early detection, and resource allocation are needed for older women in China.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jog.70413","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:20:01Z","timestamp":1789705201000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cervical, Uterine, and Ovarian Cancers in Chinese Women Aged 55\u2009Years and Older: Burden, Temporal Trends, Risk Attribution, and Future Projections From the Global Burden of Disease Study 2021"],"prefix":"10.1111","volume":"52","author":[{"given":"Xin","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Gynecology Kaifeng Maternal and Child Health Center  Kaifeng Henan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Gynecology Kaifeng Maternal and Child Health Center  Kaifeng Henan China"},{"name":"Department of Gynecology The Fifth Affiliated Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhan","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Gynecology The Fifth Affiliated Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenhui","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Gynecology Kaifeng Maternal and Child Health Center  Kaifeng Henan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shang","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Gynecology Zhengzhou Central Hospital Affiliated to Zhengzhou University  Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afad102"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874609816666230516150701"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0291718"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12939-023-01983-7"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2023.101860"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)00367-2"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(25)01637-X"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol32030122"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.1226779"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-024-01792-7"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2026.01.014"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S375643"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43587-025-00935-w"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-023-15945-9"},{"issue":"4","key":"e_1_2_13_16_1","first-page":"e58081","article-title":"Prevalence of High\u2010Risk Human Papillomavirus Infection, Associated Risk Factors, and Relationship With Cervical Precancerous Lesions in Perimenopausal and Older Women in an Area With High Cervical Cancer Incidence in China","volume":"16","author":"Zhang R.","year":"2024","journal-title":"Cureus"},{"issue":"10","key":"e_1_2_13_17_1","first-page":"e71359","article-title":"Prognostic Factors for Cervical Cancer in Asian Populations: A Scoping Review of Research From 2013 to 2023","volume":"16","author":"Abrar S. 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