{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T02:41:14Z","timestamp":1792636874704,"version":"4.5.0"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare surgical outcomes, postoperative complications, quality of life, and survival between laparoscopic surgery and laparotomy for cytoreductive surgery in patients with advanced ovarian cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cohort study included 60 patients with FIGO Stage III\u2013IV advanced ovarian cancer, allocated to the control group or the study group. Quality of life was measured. Overall survival (OS), disease\u2010free survival (DFS), and progression\u2010free survival (PFS) were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Laparoscopic surgery significantly reduced operative time, blood loss, time to bowel recovery, and chemotherapy initiation. It also resulted in higher lymph node yield and optimal cytoreduction rate. Postoperative complication rates, including hypokalemia, hypoproteinemia, wound infection, and venous thrombosis, were significantly lower in the laparoscopic group. Quality of life improved significantly post\u2010treatment in the laparoscopic group. Five\u2010year OS rates were 75.0% vs. 51.9% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.055), DFS rates were 75.0% vs. 51.9% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.057), and PFS rates were 75.0% vs. 51.9% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.072) for laparoscopic and laparotomy groups, respectively. Kaplan\u2013Meier analysis showed trends favoring the laparoscopic group, with OS approaching statistical significance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Laparoscopic cytoreductive surgery in advanced ovarian cancer improves perioperative outcomes, reduces complications, and enhances postoperative recovery while maintaining comparable long\u2010term survival outcomes to laparotomy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jog.70516","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:32:17Z","timestamp":1792456337000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Laparoscopic Versus Laparotomy for Cytoreductive Surgery in Advanced Ovarian Cancer: A Prospective Cohort Study Comparing Surgical Outcomes, Postoperative Complications, Quality of Life, and Survival"],"prefix":"10.1111","volume":"52","author":[{"given":"Guiyan","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Hospital Office, Hainan Branch Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University  Sanya Hainan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiali","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Fourth Affiliated Hospital of Guangxi Medical University  Liuzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9979-4773","authenticated-orcid":false,"given":"Yanli","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Hospital Office, Hainan Branch Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University  Sanya Hainan China"},{"name":"Department of Gynecology, Hainan Branch Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University  Sanya Hainan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,19]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-024-00881-3"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32552-2"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc-2019-000682"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2103294"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc-2020-001640"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol31090417"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13048-021-00793-1"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.27553"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.46325"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdz062"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1808424"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001851"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15245726"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2024.08.011"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1221096"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-024-16246-0"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12113296"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-023-00617-9"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2014.04.013"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2016.01.017"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.10.922"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.07.016"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2013.12.028"},{"key":"e_1_2_13_26_1","first-page":"9","article-title":"Laparoscopic Predictability of Minimally Invasive Interval Debulking in Advanced Ovarian Cancer: The MIID\u2010SOC Trial","volume":"183","author":"Costales A. 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