{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T02:40:33Z","timestamp":1792636833771,"version":"4.5.0"},"reference-count":16,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To examine how clinicopathologic reassignment under FIGO 2023 alters risk grouping and five\u2010year survival patterns among patients staged as early disease by FIGO 2009 when molecular classifiers are unavailable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The cohort comprised 351 patients treated with primary surgery from June 2010 through May 2019. All cases contributed to the restaging analysis; one case with contradictory survival coding was omitted from time\u2010to\u2010event analyses, leaving 350 evaluable patients. Five\u2010year survival was described with Kaplan\u2013Meier estimates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Stage migration occurred in 81 of 351 patients (23.1%): 75 (21.4%) were upstaged and 6 (1.7%) were downstaged; 222 (63.2%) underwent substage refinement. In the 295\u2010patient early\u2010stage cohort, FIGO 2009 showed no stage I\u2010to\u2010II survival gradient (96.7% vs. 100.0%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.440), whereas reassignment under FIGO 2023 separated stage I from stage II (99.0% vs. 91.9%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Among 277 FIGO 2009 stage I patients, 74 were upstaged; 8 of 9 deaths occurred in the upstaged group (five\u2010year overall survival, 89.0% vs. 99.5%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Among the 75 upstaged stage I cases, 66 (88.0%) followed FIGO 2023 IC\/IIC pathways defined by aggressive histology, whereas all 9 patients reassigned to IIB had substantial LVSI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Clinicopathologic FIGO 2023 restaging redistributed adverse outcomes from former stage I into stage II and showed greater five\u2010year overall survival separation. The findings apply to the clinicopathologic framework and do not constitute validation of molecularly integrated staging.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jog.70529","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:55:04Z","timestamp":1791417304000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Early\u2010Stage Risk Redistribution After Clinicopathologic Restaging From\n                    <scp>FIGO<\/scp>\n                    2009 to\n                    <scp>FIGO<\/scp>\n                    2023 in Endometrial Cancer"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6416-3712","authenticated-orcid":false,"given":"Yue","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Gynecology Dalian Women and Children's Medical Center (Group)  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Chen","sequence":"additional","affiliation":[{"name":"Baoshan Branch Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5579-3592","authenticated-orcid":false,"given":"Huali","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gynecology Dalian Women and Children's Medical Center (Group)  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6814-6858","authenticated-orcid":false,"given":"Rubing","family":"Yang","sequence":"additional","affiliation":[{"name":"Dalian Medical University  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9029-2886","authenticated-orcid":false,"given":"Miao","family":"Li","sequence":"additional","affiliation":[{"name":"Dalian Medical University  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5728-6674","authenticated-orcid":false,"given":"Yating","family":"Zhang","sequence":"additional","affiliation":[{"name":"Dalian Medical University  Dalian Liaoning 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