{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:33:01Z","timestamp":1790263981630,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,7,24]],"date-time":"2013-07-24T00:00:00Z","timestamp":1374624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional do Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior (CAPES), Bras\u00edlia, Brazil"},{"name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais (FAPEMIG), Belo Horizonte, Brazil"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p><jats:italic>We aimed to explore the relationship between brain natriuretic peptide (BNP) levels and right ventricular (RV) function in patients with mitral stenosis (MS), and to investigate the hemodynamic parameters that predict reduction of BNP levels after percutaneous mitral valvuloplasty (PMV)<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Few studies have evaluated BNP in the context of MS, specifically the impact of the RV stroke work (RVSW) on serum BNP levels has not been defined<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:italic>Thirty patients with symptomatic rheumatic MS in sinus rhythm who were referred for a PMV were enrolled. Right and left heart pressures were obtained before and after valvuloplasty. RVSW index (RVSWI) was calculated by cardiac catheterization<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:italic>Basal BNP levels were elevated in MS patients and correlated with several hemodynamic parameters including pulmonary pressure, pulmonary vascular resistance index, cardiac index (CI), and RVSWI. In multivariate analysis, CI and RVSWI were independent predictors of raised basal BNP levels. PMV resulted in a significant decrease in the RVSWI with a concurrent increase in CI (2.4\u2009\u00b1\u20090.43 to 2.9\u2009\u00b1\u20090.8\u2009L\/min\/m<jats:sup>2<\/jats:sup>, P\u2009=\u20090.010). Overall, plasma BNP levels significantly decreased from 124 (63\/234) to 73 (48\/148)\u2009pg\/ml postvalvuloplasty. Multivariate analysis revealed that the reduction of left atrial (LA) pressure post\u2010PMV was an independent predictor of change in BNP levels<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:italic>Elevated baseline BNP level in MS patients was independently associated with CI and RVSWI. Plasma BNP levels were reduced after successful PMV, which was associated with the reduction of the LA pressure<\/jats:italic>. (J Interven Cardiol 2013;26:501\u2010508)<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12050","type":"journal-article","created":{"date-parts":[[2013,7,24]],"date-time":"2013-07-24T18:50:59Z","timestamp":1374691859000},"page":"501-508","source":"Crossref","is-referenced-by-count":12,"title":["The Impact of Right Ventricular Stroke Work on B\u2010<scp>T<\/scp>ype Natriuretic Peptide Levels in Patients With Mitral Stenosis Undergoing Percutaneous Mitral Valvuloplasty"],"prefix":"10.1111","volume":"26","author":[{"given":"WILLIAM A. M.","family":"ESTEVES","sequence":"first","affiliation":[{"name":"Post\u2010Graduate Program in Infectious Diseases and Tropical Medicine, School of Medicine Federal University of Minas Gerais Belo Horizonte MG Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LUCAS","family":"LODI\u2010JUNQUEIRA","sequence":"additional","affiliation":[{"name":"Hospital das Cl\u00ednicas, School of Medicine Federal University of Minas Gerais Belo Horizonte MG Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CIRILO P. FONSECA","family":"NETO","sequence":"additional","affiliation":[{"name":"Hospital das Cl\u00ednicas, School of Medicine Federal University of Minas Gerais Belo Horizonte MG Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TIMOTHY C.","family":"TAN","sequence":"additional","affiliation":[{"name":"Cardiac Ultrasound Laboratory, Massachusetts General Hospital Harvard Medical School Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BRUNO R.","family":"NASCIMENTO","sequence":"additional","affiliation":[{"name":"Hospital das Cl\u00ednicas, School of Medicine Federal University of Minas Gerais Belo Horizonte MG Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PRAVEEN","family":"MEHROTRA","sequence":"additional","affiliation":[{"name":"Cardiac Ultrasound Laboratory, Massachusetts General Hospital Harvard Medical School Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MARCIA M.","family":"BARBOSA","sequence":"additional","affiliation":[{"name":"Hospital das Cl\u00ednicas, School of Medicine Federal University of Minas Gerais Belo Horizonte MG Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANTONIO LUIZ P.","family":"RIBEIRO","sequence":"additional","affiliation":[{"name":"Post\u2010Graduate Program in Infectious Diseases and Tropical Medicine, School of Medicine Federal University of Minas Gerais Belo Horizonte MG Brazil"},{"name":"Hospital das Cl\u00ednicas, School of Medicine Federal University of Minas Gerais Belo Horizonte MG Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MARIA CARMO P.","family":"NUNES","sequence":"additional","affiliation":[{"name":"Post\u2010Graduate Program in Infectious Diseases and Tropical Medicine, School of Medicine Federal University of Minas Gerais Belo Horizonte MG Brazil"},{"name":"Hospital das Cl\u00ednicas, School of Medicine Federal University of Minas Gerais Belo Horizonte MG Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-52-4-741"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(62)90171-6"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.30.2.188"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-006-9174-8"},{"key":"e_1_2_8_6_1","first-page":"453","article-title":"Effects of percutaneous balloon mitral valvuloplasty on plasma B\u2010type natriuretic peptide in rheumatic mitral stenosis with and without atrial fibrillation","volume":"14","author":"Shang YP","year":"2005","journal-title":"J Heart Valve Dis"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-097X.2010.00968.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2009.206607"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00452-X"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/heart.86.1.27"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.60.4.299"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(96)90476-9"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.2000.2296"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2009.04.027"},{"key":"e_1_2_8_15_1","first-page":"89P","article-title":"Reproducibility of the indirect (CO2) Fick method for the calculation of cardiac output","volume":"222","author":"Godfrey S","year":"1972","journal-title":"J Physiol"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)37390-8"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1810280206"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.01.046"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI115146"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.48.579"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2008.07.014"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(92)90413-P"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000222768.15100.00"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2008.03.050"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(85)80080-2"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1010647524678"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2008.09.006"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.03.009"},{"key":"e_1_2_8_29_1","first-page":"735","article-title":"N\u2010terminal proBNP plasma levels correlate with severity of mitral stenosis","volume":"14","author":"Iltumur K","year":"2005","journal-title":"J Heart Valve Dis"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.1_suppl.78S"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2004.06.002"}],"container-title":["Journal of Interventional Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoic.12050","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoic.12050","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joic.12050","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T14:40:18Z","timestamp":1696516818000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joic.12050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,24]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1111\/joic.12050"],"URL":"https:\/\/doi.org\/10.1111\/joic.12050","archive":["Portico"],"relation":{},"ISSN":["0896-4327","1540-8183"],"issn-type":[{"value":"0896-4327","type":"print"},{"value":"1540-8183","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,24]]}}}