{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:43:21Z","timestamp":1761561801065},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,9,30]],"date-time":"2013-09-30T00:00:00Z","timestamp":1380499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p><jats:italic>The aim of this study was to examine the angiographic result and its outcome predictors using the combination of paclitaxel\u2010eluting balloon (PEB) and Genous stent<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>This approach to treat coronary stenoses is a logical strategy to strike a balance between minimizing restenosis and stent thrombosis<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:italic>From November 2010 to June 2012, 40 symptomatic patients with 44 de novo coronary lesions of diameter stenosis \u226550% were treated with the combination of PEB and Genous stents. Angiographic and clinical follow\u2010up were intended at 6 and 9 months, respectively<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:italic>The mean age of patients was 61\u2009\u00b1\u200911 years, with male predominance (83%). Diabetes mellitus and end\u2010stage renal failure on peritoneal dialysis were found in 15 (38%) and 10 (25%) patients, respectively. Patients received dual antiplatelet therapy for 5.1\u2009\u00b1\u20091.5 months post procedure. The size and length of PEB used was larger than the stents (3.13\u2009\u00b1\u20090.46\u2009mm and 28\u2009\u00b1\u20099\u2009mm vs. 2.98\u2009\u00b1\u20090.36\u2009mm and 23\u2009\u00b1\u20097\u2009mm). Restudy angiography was performed on 41 (95%) lesions in 37 (93%) patients at 5.9\u2009\u00b1\u20091.7 months. Angiographic restenosis was seen in 5 (12%) lesions, and significantly associated with diabetes mellitus and dialysis dependency; the late lumen loss was 0.38\u2009\u00b1\u20090.37\u2009mm. At 9\u2010month follow\u2010up, no stent thrombosis was observed<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:italic>The use of PEB combined with Genous stent is associated with a reasonably low restenosis and late lumen loss, whereas diabetes mellitus and renal failure with dialysis are poor predictors of angiographic restenosis<\/jats:italic>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12072","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T01:48:52Z","timestamp":1381542532000},"page":"556-560","source":"Crossref","is-referenced-by-count":3,"title":["Combined Paclitaxel\u2010<scp>E<\/scp>luting Balloon and Genous Cobalt\u2013<scp>C<\/scp>hromium Alloy Stent Utilization in De Novo Coronary Stenoses (PEGASUS)"],"prefix":"10.1111","volume":"26","author":[{"given":"MAN\u2010HONG","family":"JIM","sequence":"first","affiliation":[{"name":"Cardiac Medical Unit Grantham Hospital Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RAYMOND CHI\u2010YAN","family":"FUNG","sequence":"additional","affiliation":[{"name":"Cardiac Medical Unit Grantham Hospital Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KAI\u2010HANG","family":"YIU","sequence":"additional","affiliation":[{"name":"Division of Cardiology Queen Mary Hospital Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ANDREW KEI\u2010YAN","family":"NG","sequence":"additional","affiliation":[{"name":"Cardiac Medical Unit Grantham Hospital Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CHUNG\u2010WAH","family":"SIU","sequence":"additional","affiliation":[{"name":"Division of Cardiology Queen Mary Hospital Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KATHERINE YU\u2010YAN","family":"FAN","sequence":"additional","affiliation":[{"name":"Cardiac Medical Unit Grantham Hospital Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.693739"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2009.09.015"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2011.05.011"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV3I3A64"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa061254"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV7I6A114"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.09.011"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.685313"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.100.18.1872"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.11.063"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.07.084"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012843"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032441"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2011.226563"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01745-X"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.11.009"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.108.828954"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.109.919936"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.10.018"}],"container-title":["Journal of Interventional Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoic.12072","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoic.12072","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joic.12072","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T02:03:55Z","timestamp":1696471435000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joic.12072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,30]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["10.1111\/joic.12072"],"URL":"https:\/\/doi.org\/10.1111\/joic.12072","archive":["Portico"],"relation":{},"ISSN":["0896-4327","1540-8183"],"issn-type":[{"value":"0896-4327","type":"print"},{"value":"1540-8183","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,30]]}}}