{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:17:03Z","timestamp":1791461823465,"version":"4.3.4"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,12,13]],"date-time":"2013-12-13T00:00:00Z","timestamp":1386892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the periprocedural characteristics and outcomes of patients supported with Impella 2.5 prior to percutaneous coronary intervention (pre\u2010PCI) versus those who received it after PCI (post\u2010PCI) in the setting of cardiogenic shock (CS) complicating an acute myocardial infarction (AMI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Early mechanical circulatory support may improve outcome in the setting of CS complicating an AMI. However, the optimal timing to initiate hemodynamic support has not been well characterized.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from 154 consecutive patients who underwent PCI and Impella 2.5 support from 38 US hospitals participating in the USpella Registry were included in our study. The primary end\u2010point was survival to discharge. Secondary end\u2010points included assessment of patients' hemodynamics and in\u2010hospital complications. A multivariate regression model was used to identify independent predictors for mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Both groups were comparable except for diabetes (P\u2009=\u20090.02), peripheral vascular disease (P\u2009=\u20090.008), chronic obstructive pulmonary disease (P\u2009=\u20090.05), and prior stroke (P\u2009=\u20090.04), all of which were more prevalent in the pre\u2010PCI group. Patients in the pre\u2010PCI group had more lesions (P\u2009=\u20090.006) and vessels (P\u2009=\u20090.01) treated. These patients had also significantly better survival to discharge compared to patients in the post\u2010PCI group (65.1% vs.40.7%, P\u2009=\u20090.003). Survival remained favorable for the pre\u2010PCI group after adjusting for potential confounding variables. Initiation of support prior to PCI with Impella 2.5 was an independent predictor of in\u2010hospital survival (Odds ratio 0.37, 95% confidence interval: 0.17\u20130.79, P\u2009=\u20090.01) in multivariate analysis. The incidence of in\u2010hospital complications included in the secondary end\u2010point was similar between the 2 groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results of our study suggest that early initiation of hemodynamic support prior to PCI with Impella 2.5 is associated with more complete revascularization and improved survival in the setting of refractory CS complicating an AMI. (J Interven Cardiol 2014;27:1\u201311)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joic.12080","type":"journal-article","created":{"date-parts":[[2013,12,13]],"date-time":"2013-12-13T05:53:30Z","timestamp":1386914010000},"page":"1-11","source":"Crossref","is-referenced-by-count":345,"title":["The Current Use of Impella 2.5 in Acute Myocardial Infarction Complicated by Cardiogenic Shock: Results from the USpella Registry"],"prefix":"10.1111","volume":"27","author":[{"given":"WILLIAM W.","family":"O'NEILL","sequence":"first","affiliation":[{"name":"Henry Ford Hospital Detroit Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"THEODORE","family":"SCHREIBER","sequence":"additional","affiliation":[{"name":"Detroit Medical Center Detroit Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DAVID H. W.","family":"WOHNS","sequence":"additional","affiliation":[{"name":"Spectrum Health Grand Rapids Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CHARANJIT","family":"RIHAL","sequence":"additional","affiliation":[{"name":"Mayo Clinic Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SRIHARI S.","family":"NAIDU","sequence":"additional","affiliation":[{"name":"Winthrop University Hospital Mineola New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANDREW B.","family":"CIVITELLO","sequence":"additional","affiliation":[{"name":"Texas Heart Institute Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SIMON R.","family":"DIXON","sequence":"additional","affiliation":[{"name":"Beaumont Hospital Royal Oak Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOSEPH M.","family":"MASSARO","sequence":"additional","affiliation":[{"name":"Harvard Research Institute Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BRIJESHWAR","family":"MAINI","sequence":"additional","affiliation":[{"name":"Pinnacle Health Medical Center Wormleysburg Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. MAGNUS","family":"OHMAN","sequence":"additional","affiliation":[{"name":"Duke University Medical Center Durham North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-149-9-200811040-00005"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.08.007"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.814947"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.05.065"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.098194"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1208410"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0b013e31824a67af"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn602"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2013.02.020"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-012-0523-4"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.10.037"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00876-7"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.112.967224"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31821e89b5"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(03)01051-9"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.11.014"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.23006"}],"container-title":["Journal of Interventional Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoic.12080","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joic.12080","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/joic.12080","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joic.12080","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T10:31:42Z","timestamp":1696501902000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joic.12080"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,13]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["10.1111\/joic.12080"],"URL":"https:\/\/doi.org\/10.1111\/joic.12080","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.727617160.793532147","asserted-by":"object"}]},"ISSN":["0896-4327","1540-8183"],"issn-type":[{"value":"0896-4327","type":"print"},{"value":"1540-8183","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,13]]}}}