{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:25:53Z","timestamp":1740137153547,"version":"3.37.3"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,4,29]],"date-time":"2014-04-29T00:00:00Z","timestamp":1398729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["HL97074"],"award-info":[{"award-number":["HL97074"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"crossref","award":["13IRG14560018"],"award-info":[{"award-number":["13IRG14560018"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p><jats:italic>To determine the impact of coronary collaterals in stable angina<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Whether spontaneously visible coronary collaterals are associated with long\u2010term clinical outcomes in stable angina remains unclear<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:italic>We prospectively enrolled patients with stable angina referred for coronary angiography and followed them clinically for 1 year<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:italic>A total of 1,134 consecutive patients were enrolled, and of these, 550 had at least single\u2010vessel coronary artery disease (CAD) and were included. Patients with collaterals had more congestive heart failure (16% vs. 9%, P\u2009=\u20090.023), peripheral vascular disease (22% vs. 15%, P\u2009=\u20090.044), and 2\u2010vessel (36% vs. 26%) and 3\u2010vessel (28% vs. 10%) CAD compared to those without collaterals (P\u2009&lt;\u20090.001). Patients with collaterals were less likely to undergo percutaneous intervention at the time of the index angiogram (32% vs. 61%, P\u2009&lt;\u20090.001). At 1 year, there were no differences in angina (HR 0.74, 95% CI 0.50\u20131.10; P\u2009=\u20090.141), myocardial infarction (MI) (HR 1.22, 95% CI 0.46\u20133.21; P\u2009=\u20090.691), revascularization (HR 0.84, 95% CI 0.55\u20131.30; P\u2009=\u20090.431), death (HR 1.83, 95% CI 0.63\u20135.31; P\u2009=\u20090.269), or the combined end\u2010point of death, MI, and revascularization (HR 0.87, 95% CI 0.61\u20131.24; P\u2009=\u20090.426) between patients with and without collaterals. When analyzed according to collateral grade, patients with Rentrop grade 1 had less angina (HR 0.48, 95% CI 0.26\u20130.89; P\u2009=\u20090.019)<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:italic>At 1 year, there was no difference in adverse events between patients with or without collaterals. The presence of Rentrop grade 1 collaterals, however, was associated with significantly less angina<\/jats:italic>. (J Interven Cardiol 2014;27:225\u2013232)<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12124","type":"journal-article","created":{"date-parts":[[2014,4,29]],"date-time":"2014-04-29T11:36:43Z","timestamp":1398771403000},"page":"225-232","source":"Crossref","is-referenced-by-count":2,"title":["The Association of Angiographic Collaterals with Long\u2010Term Clinical Outcomes in Patients with Chronic Stable Angina"],"prefix":"10.1111","volume":"27","author":[{"given":"ROBERT C.","family":"SCHUTT","sequence":"first","affiliation":[{"name":"Department of Medicine University of Virginia Charlottesville Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SHIU M.","family":"YOUNG","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Virginia Charlottesville Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LING","family":"LIU","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Virginia 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