{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T06:15:39Z","timestamp":1696572939251},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,7,24]],"date-time":"2014-07-24T00:00:00Z","timestamp":1406160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p><jats:italic>We aimed to compare early and late clinical outcomes in diabetic and nondiabetic patients who underwent saphenous vein graft (SVG) percutaneous coronary interventions (PCI) with the use of drug\u2010eluting stents (DES)<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Patients with diabetes mellitus are shown to have less favorable outcomes after SVG intervention with the use of bare metal stents. In the DES era, the impact of diabetes mellitus on restenosis and clinical outcomes post\u2010SVG intervention is not clearly defined<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:italic>From our institutional PCI registry database, we retrospectively analyzed 477 consecutive patients with prior coronary artery bypass graft surgery undergoing SVG PCI with the implantation of DES stratified by the presence or absence of diabetes mellitus. The primary end\u2010point was 1\u2010year major adverse cardiac event (MACE) rate, defined as death, Q wave myocardial infarction, and target lesion revascularization<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:italic>Baseline clinical characteristics, including mean graft age (120\u2009\u00b1\u200977 vs. 131\u2009\u00b1\u200986 months, P\u2009=\u20090.14), were similar between groups, save for a higher prevalence of systemic hypertension and chronic renal insufficiency, and higher body mass index in the diabetic group. Among the 604 SVG lesions treated with DES, the angiographic and procedural characteristics were well matched between groups except for the higher rate of distal protection device use (32% vs. 29%, P\u2009=\u20090.007) in the diabetic group. The rates of 1\u2010year MACE (21% vs. 15%, P\u2009=\u20090.12) and all\u2010cause mortality (7.6% vs. 6.7%, P\u2009=\u20090.86) were similar between groups. After adjustment for the relevant clinical co\u2010variables, diabetic status was not associated with the composite end\u2010point<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:italic>In conclusion, DES, when used for the treatment of vein graft lesions, equate the short\u2010 and long\u2010term outcomes between diabetic and nondiabetic patients, suggesting that DES should be considered the default stent in diabetic populations undergoing PCI for the treatment of SVG lesions<\/jats:italic>. (J Interven Cardiol 2014;27:391\u2013398)<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12136","type":"journal-article","created":{"date-parts":[[2014,7,24]],"date-time":"2014-07-24T17:19:58Z","timestamp":1406222398000},"page":"391-398","source":"Crossref","is-referenced-by-count":4,"title":["The Impact of Diabetes Mellitus on Long\u2010Term Clinical Outcomes After Percutaneous Coronary Saphenous Vein Graft Interventions in the Drug\u2010Eluting Stent Era"],"prefix":"10.1111","volume":"27","author":[{"given":"LAKSHMANA K.","family":"PENDYALA","sequence":"first","affiliation":[{"name":"Division of Cardiology MedStar Washington Hospital Center Washington District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOSHUA P.","family":"LOH","sequence":"additional","affiliation":[{"name":"Division of Cardiology MedStar Washington Hospital Center Washington District of 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