{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T18:59:09Z","timestamp":1789498749300,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,6,16]],"date-time":"2015-06-16T00:00:00Z","timestamp":1434412800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005090","name":"Beijing Nova Program","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005090","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Union Youth Science & Research Fund","award":["2012-XHQN03"],"award-info":[{"award-number":["2012-XHQN03"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Demonstrate the benefits of percutaneous atrial septal defect (ASD) closure under guidance of transthoracic echocardiography (TTE) without fluoroscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From February 2013 to April 2014, 127 consecutive patients with an isolated type II ASD were recruited to undergo percutaneous closure under either TTE (n\u2009=\u200960, TTE group) or TEE (n\u2009=\u200967, TEE group) guidance. The TTE group received local anesthesia or sedation with propofol, and the TEE group received general anesthesia with endotracheal intubation. Follow\u2010up examinations were performed for both groups at 1 month, 3 months, 6 months, and 1 year after discharge and annually thereafter.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The TTE group had a significantly shorter procedure time and respirator ventilation duration than the TEE group. The dose of propofol required, the cost, and the pharyngeal complication rate were significantly lower in the TTE group than in the TEE group. The median follow\u2010up of 11.6 months was uneventful in all patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Percutaneous ASD closure with TTE guidance as the only imaging tool avoids fluoroscopy, endotracheal intubation, and probe insertion and is associated with a satisfactory procedural success rate and lower costs. This procedure is a safe and reliable treatment for ASD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12214","type":"journal-article","created":{"date-parts":[[2015,6,16]],"date-time":"2015-06-16T09:09:32Z","timestamp":1434445772000},"page":"390-395","source":"Crossref","is-referenced-by-count":42,"title":["Percutaneous Closure of Atrial Septal Defects Under Transthoracic Echocardiography Guidance Without Fluoroscopy or Intubation in Children"],"prefix":"10.1111","volume":"28","author":[{"given":"Xiang\u2010Bin","family":"Pan","sequence":"first","affiliation":[{"name":"National Center for Cardiovascular Disease China and Fuwai Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Bin","family":"Ou\u2010yang","sequence":"additional","affiliation":[{"name":"National Center for Cardiovascular Disease China and Fuwai Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun\u2010Jing","family":"Pang","sequence":"additional","affiliation":[{"name":"National Center for Cardiovascular Disease China and Fuwai Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng\u2010Wen","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Center for Cardiovascular Disease China and Fuwai Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shou\u2010Zheng","family":"Wang","sequence":"additional","affiliation":[{"name":"National Center for Cardiovascular Disease China and Fuwai Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 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