{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T19:34:10Z","timestamp":1776886450787,"version":"3.51.2"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Small vessel disease (SMD) remains a major challenge because of the increased risk of restenosis. We sought to assess the efficacy and safety of a paclitaxel\u2010eluting balloon (PEB) in patients with SMD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>One\u2010hundred and four patients with native coronary lesions in small vessels treated by using a PEB were included in this prospective multicenter registry. In each case, after regular balloon dilatation, a larger PEB was inflated for a minimum of 45\u201360 seconds. Patients were 65\u2009\u00b1\u200910 years old, 43% diabetic, and 58% presented acutely. Angiographic success was 93% (7% bailout BMS implantation due to coronary dissection). The rate of major adverse cardiac events (MACE) at 12 months was 4.8% (1.9% cardiac death, 1.0% MI, and 2.9% TLR). One definite stent thrombosis was reported at 6 months in a patient with bailout BMS implantation. At 7 months, late loss was 0.31\u2009\u00b1\u20090.2\u2009mm. Bail\u2010out BMS after DEB use, was an independent predictor of MACE, HR 18.74, 95%CI (2.58\u2013135.84) and TLR, HR 30.99, 95%CI (2.79\u2013344.07).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The use of this PEB for the treatment of SMD provides excellent 1\u2010year outcomes with only 4.8% MACE. The need for a bailout BMS was a strong predictor of MACE and TLR. (J Interven Cardiol 2015;28:430\u2013438)<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12227","type":"journal-article","created":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T10:14:30Z","timestamp":1442571270000},"page":"430-438","source":"Crossref","is-referenced-by-count":35,"title":["Treatment of Small Vessel Disease With the Paclitaxel Drug\u2010Eluting Balloon: 6\u2010Month Angiographic and 1\u2010Year Clinical Outcomes of the Spanish Multicenter Registry"],"prefix":"10.1111","volume":"28","author":[{"given":"Beatriz","family":"Vaquerizo","sequence":"first","affiliation":[{"name":"Interventional Cardiology Unit, Hospital Sant Pau Barcelone Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faustino","family":"Miranda\u2010Guardiola","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit Hospital del Mar Barcelone 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