{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T21:31:51Z","timestamp":1780781511056,"version":"3.54.1"},"reference-count":6,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,1,5]],"date-time":"2016-01-05T00:00:00Z","timestamp":1451952000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>We evaluate the prevalence of complications and failure rates between the most commonly used \u201cactive\u201d anchoring vascular closure device (VCD), AngioSeal\u2122 and the \u201cpassive\u201d anchoring VCD, Mynx\u2122, in all\u2010comers undergoing percutaneous coronary intervention (PCI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 4,074 patients between 2008 and 2014, representing an era when both devices were available, were included. Thirty\u2010two percent were acute coronary syndromes (37% STEMI). VCD choice was at the operator's discretion and included AngioSeal (n\u2009=\u20092,910) or Mynx (1,164). Cardiogenic shock or patients receiving intra\u2010aortic balloon pumps were excluded. Safety was assessed by vascular complications defined as either vascular injury (perforation, dissection, acute limb ischemia, arteriovenous fistula, pseudoaneurysm with thrombin injection, or surgical repair) or access\u2010site bleed (hemoglobin droP &gt;3\u2009g\/dL requiring transfusion, retroperitoneal bleed, or hematoma &gt;5\u2009cm, or the composite of both. Efficacy was evaluated by device failure and defined as inability to achieve immediate hemostasis or use of additional hemostatic mechanisms. Outcomes at 30\u2010days were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Groups (AngioSeal vs Mynx) were fairly balanced with regards to bleeding risk factors of gender (male, 65% vs 66%), body mass index (30\u2009\u00b1\u20096 vs 30\u2009\u00b1\u20097), heart failure class III\/IV (5% vs 6%), chronic kidney disease (15% vs 17%), use of glycoprotein IIb\/IIIa inhibitor (5% vs 4%), or bivalirudin (86% vs 88%), all P &gt;0.5. The AngioSeal group was slightly younger (64\u2009\u00b1\u200912 vs 65\u2009\u00b1\u200912, P\u2009&lt;\u20090.001) with less peripheral arterial disease (11.3% vs 13.9%, P\u2009=\u20090.03), and increased 7F sheath use compared with Mynx (59% vs 22%, P\u2009&lt;\u20090.001). Safety and efficacy outcomes were similar between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>AngioSeal and Mynx appear to be equally safe and efficacious VCDs following PCI. The passive anchoring system may prove desirable as no intra\u2010arterial anchor remains upon device removal. (J Interven Cardiol 2016;29:108\u2013112)<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12264","type":"journal-article","created":{"date-parts":[[2016,1,5]],"date-time":"2016-01-05T13:16:32Z","timestamp":1451999792000},"page":"108-112","source":"Crossref","is-referenced-by-count":13,"title":["Active Versus Passive Anchoring Vascular Closure Devices Following Percutaneous Coronary Intervention: A Safety and Efficacy Comparative Analysis"],"prefix":"10.1111","volume":"29","author":[{"given":"Nevin C.","family":"Baker","sequence":"first","affiliation":[{"name":"Department of Interventional Cardiology MedStar Washington Hospital Center Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo O.","family":"Escarcega","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology MedStar Washington Hospital Center Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Lipinski","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology MedStar Washington Hospital Center Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco A.","family":"Magalhaes","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology MedStar Washington Hospital Center Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Koifman","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology MedStar Washington Hospital Center Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarkis","family":"Kiramijyan","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology MedStar Washington Hospital Center Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smita I.","family":"Negi","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology MedStar Washington Hospital Center Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Torguson","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology MedStar Washington Hospital Center Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron","family":"Waksman","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology MedStar Washington Hospital Center Washington District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.06.048"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.3.350"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21353"},{"key":"e_1_2_6_5_1","first-page":"243","article-title":"A meta\u2010analysis of percutaneous vascular closure devices after diagnostic catheterization and percutaneous coronary intervention","volume":"16","author":"Vaitkus PT.","year":"2004","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2009.12.027"},{"key":"e_1_2_6_7_1","first-page":"175","article-title":"Vascular complications after percutaneous coronary intervention following hemostasis with the Mynx vascular closure device versus the AngioSeal vascular closure device","volume":"22","author":"Azmoon S","year":"2010","journal-title":"J Invasive Cardiol"}],"container-title":["Journal of Interventional Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoic.12264","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoic.12264","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joic.12264","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T12:55:40Z","timestamp":1695732940000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joic.12264"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,5]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1111\/joic.12264"],"URL":"https:\/\/doi.org\/10.1111\/joic.12264","archive":["Portico"],"relation":{},"ISSN":["0896-4327","1540-8183"],"issn-type":[{"value":"0896-4327","type":"print"},{"value":"1540-8183","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,5]]}}}