{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T01:59:09Z","timestamp":1791165549409,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T00:00:00Z","timestamp":1464652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>This observational study assessed the 9\u2010month clinical outcomes in patients with coronary bifurcation lesions suitable for drug\u2010coated balloon (DCB) angioplasty. It was the intention to use DCB's without additional stenting (DCB\u2010only strategy) in selected patients for this chosen strategy. Bail\u2010out main branch (MB) and\/or side branch (SB) stenting, however, were permissible when flow limiting dissections or excessive recoil occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>A multitude of interventional strategies have been studied to treat bifurcation lesions. With the availability of DCB angioplasty, investigators have been using this interventional tool with the optional implantation of bare metal stents (BMS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study is an international, prospective, multicenter registry enrolling patients with coronary bifurcation lesions including a side branch \u22652\u2009mm in diameter. Patients with stable angina and documented ischemia or selected forms of unstable angina due to a culprit bifurcation lesion of any Medina classification type were recruited. The primary endpoint was clinically driven target\u2010lesion revascularization (TLR) at 9 months. Secondary endpoints included 9\u2010month major adverse cardiac events (death, myocardial infarction, or TLR), technical success, in\u2010hospital outcomes and vessel thrombosis rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total 127 patients 66.1\u2009\u00b1\u200910.1 years of age were enrolled. Demographic characteristics were 80.3% (102\/127) male gender, 31.5% (40\/127) diabetes, 91.3% (116\/127) hypertension, 7.1% (9\/127) ST\u2010elevation myocardial infarction (STEMI), and 9.4% (12\/127) non ST\u2010elevation myocardial infarction (NSTEMI). The 130 lesions were treated with 184 DCB's and 64 BMS. In 53.8% (70\/130) of all lesions the DCB\u2010only strategy could be used while 34.6% (45\/130) of lesions had at least 1 stent (BMS) in the main branch, 8.5% (11\/130) had at least 1 stent in the side branch and 3.1% (4\/130) needed at least 1 stent in the main and side branch. 94.5% patients (121\/127) were available for follow\u2010up after 9.8\u2009\u00b1\u20092.0 months. The TLR rate was 4.6% in the absence of any thrombotic events in the treated vessels whereas the 9\u2010month MACE rate was 6.2%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This observational study suggests that the DCB\u2010only strategy is safe and effective to treat selected bifurcations while benefiting from a shortened dual antiplatelet therapy (DAPT).<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12301","type":"journal-article","created":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T08:16:48Z","timestamp":1464682608000},"page":"348-356","source":"Crossref","is-referenced-by-count":37,"title":["Results From the International Drug Coated Balloon Registry for the Treatment of Bifurcations. Can a Bifurcation Be Treated Without Stents?"],"prefix":"10.1111","volume":"29","author":[{"given":"Leonhard","family":"Bruch","sequence":"first","affiliation":[{"name":"Unfallkrankenhaus Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariusz","family":"Zadura","sequence":"additional","affiliation":[{"name":"Klinikum Karlsburg der Klinikgruppe Dr. Guth GmbH and Co. KG Karlsburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Waliszewski","sequence":"additional","affiliation":[{"name":"Medical Scientific Affairs B.Braun Vascular Systems Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeljko","family":"Platonic","sequence":"additional","affiliation":[{"name":"Clinical Hospital Center Rijeka Rijeka Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaako","family":"Er\u00e4nen","sequence":"additional","affiliation":[{"name":"Pohjois\u2010Karjalan Keskussairaala 1 Kokkola Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Scheller","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum des Saarlandes Homburg\/Saar Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"G\u00f6tting","sequence":"additional","affiliation":[{"name":"Christliches Krankenhaus Quakenbr\u00fcck gGmbH Quakenbr\u00fcck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denny","family":"Herberger","sequence":"additional","affiliation":[{"name":"Medical Scientific Affairs B.Braun Vascular Systems Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cataldo","family":"Palmieri","sequence":"additional","affiliation":[{"name":"Ospedale del Cuore G. 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