{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T09:07:05Z","timestamp":1785575225778,"version":"3.56.0"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,8,22]],"date-time":"2016-08-22T00:00:00Z","timestamp":1471824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Evaluate the use of mechanical circulatory support (MCS) devices in high\u2010risk patients undergoing transcatheter aortic valve replacement (TAVR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The use of MCS devices in elderly patients with multiple comorbidities undergoing TAVR is underexplored.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients undergoing TAVR at a single tertiary academic center who required MCS during index procedure between 2008 and 2015 were included in a prospective database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>MCS was used in 9.4% (54\/577) of all TAVRs (n\u2009=\u200952 Edwards Sapien and n\u2009=\u20092 CoreValves) of which 68.5% (n\u2009=\u200937) were used as part of a planned strategy, and 31.5% (n\u2009=\u200917) were used in emergency \u201cbail\u2010out\u201d situations. IABP was the most commonly used device (87%) followed by Impella and ECMO (6% each). Among the MCS group, 22% required cardiopulmonary resuscitation during the procedure (n\u2009=\u20094 elective [11%] vs. n\u2009=\u20098 emergent [47%]) and 15% upgrade to a second device (Impella or CPB after IABP; n\u2009=\u20095 elective [14%] vs. n\u2009=\u20093 emergent [18%]). Median duration of support was 1\u2010day. Device related complications were low (4%). In\u2010hospital mortality in this extremely high\u2010risk population was 24% (13\/54) (11% [4\/37] for elective cases and 53% [9\/17] for emergency cases). Cardiogenic shock (50%) was the most common cause of in\u2010hospital death. Cumulative all\u2010cause 1\u2010year mortality was 35% (19\/54) (19% 97\/370 for elective and 71% [12\/17] for emergency cases).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Emergent use of MCS during TAVR in extremely high\u2010risk population is associated with high short and long\u2010term mortality rates. Early identification of patients at risk for hemodynamic compromise may rationalize elective utilization of MCS during TAVR.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12323","type":"journal-article","created":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T00:52:48Z","timestamp":1471913568000},"page":"513-522","source":"Crossref","is-referenced-by-count":39,"title":["Elective or Emergency Use of Mechanical Circulatory Support Devices During Transcatheter Aortic Valve Replacement"],"prefix":"10.1111","volume":"29","author":[{"given":"Vikas","family":"Singh","sequence":"first","affiliation":[{"name":"Interventional Cardiology Massachusetts General Hospital Harvard Medical School Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulla A.","family":"Damluji","sequence":"additional","affiliation":[{"name":"Cardiovascular Division University of Miami Miller School of Medicine, and the Elaine and Sydney Sussman Cardiac Catheterization Laboratory University of Miami Hospital Miami Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Mendirichaga","sequence":"additional","affiliation":[{"name":"Cardiovascular Division University of Miami Miller School of Medicine, and the Elaine and Sydney Sussman Cardiac Catheterization Laboratory University of Miami Hospital Miami Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos E.","family":"Alfonso","sequence":"additional","affiliation":[{"name":"Cardiovascular Division University of Miami Miller School of Medicine, and the Elaine and Sydney Sussman Cardiac Catheterization Laboratory University of Miami Hospital Miami Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia A.","family":"Martinez","sequence":"additional","affiliation":[{"name":"Cardiovascular Division University of Miami Miller School of Medicine, and the Elaine and Sydney Sussman Cardiac Catheterization Laboratory University of Miami Hospital Miami Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Williams","sequence":"additional","affiliation":[{"name":"Cardiovascular Division University of Miami Miller School of Medicine, and the Elaine and Sydney Sussman Cardiac Catheterization Laboratory University of Miami Hospital Miami Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan W.","family":"Heldman","sequence":"additional","affiliation":[{"name":"Cardiovascular Division University of Miami Miller School of Medicine, and the Elaine and Sydney Sussman Cardiac Catheterization Laboratory University of Miami Hospital Miami Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo J.","family":"de Marchena","sequence":"additional","affiliation":[{"name":"Cardiovascular Division University of Miami Miller School of Medicine, and the Elaine and Sydney Sussman Cardiac Catheterization Laboratory University of Miami Hospital Miami Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William W.","family":"O'Neill","sequence":"additional","affiliation":[{"name":"Cardiovascular Division Henry Ford Hospital Detroit Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauricio G.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Cardiovascular Division University of Miami Miller School of Medicine, and the Elaine and Sydney Sussman Cardiac Catheterization Laboratory University of Miami Hospital Miami Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1008232"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.09.001"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25776"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.03.036"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2009.07.005"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3810\/pgm.2013.09.2697"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1103510"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.1474"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/joic.12201"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.24303"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2015.08.020"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.24583"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25784"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.24806"}],"container-title":["Journal 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