{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T21:44:21Z","timestamp":1755035061343},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,8,8]],"date-time":"2016-08-08T00:00:00Z","timestamp":1470614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Drug\u2010eluting balloons (DEBs) have emerged as a potential alternative to current treatments of instent restenosis (ISR). The study aims to investigate the clinical outcomes of a DEB angioplasty to treat bare\u2010metal stent (BMS) ISR and drug\u2010eluting stent (DES) ISR at 1\u2010year clinical follow\u2010up period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between November 2011 and December 2014, 312 patients were diagnosed with coronary artery ISR at our hospital. A total of 426 coronary ISR lesions were treated with DEBs. The clinical outcomes, including target lesion revascularization (TLR), myocardial infarction, stroke, cardiovascular mortality, and all\u2010cause mortality were compared between the BMS\u2010ISR group and DES\u2010ISR group. Propensity score matched analysis was used to minimize bias.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average age of the patients was 64.99\u2009\u00b1\u200910.35 years, and 76.9% of the patients were male. After multivariate Cox regression analyses about 1\u2010year recurrent restenosis in DES\u2010ISR group, only end stage renal disease (ESRD) (P\u2009=\u20090.047) and previous DEB failure (P\u2009&lt;\u20090.001) were identified with significant difference. After propensity score matched analysis, the bias of baseline characteristics showed no significant difference. The DES\u2010ISR group experienced more myocardial infarctions (2.8% vs 8.3%, P\u2009=\u20090.075), more TLR (8.1% vs 15.4%, P\u2009=\u20090.051), especially at nonostial lesion (5.7% vs 14.9%, P\u2009=\u20090.030) than the BMS\u2010ISR group. Higher incidence of major cardiac cerebral adverse events happened in the DES\u2010ISR group. (11.7% vs 22.1 %, P\u2009=\u20090.038)<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>During the 1\u2010year follow\u2010up period, DEBs angioplasty for BMS\u2010ISR had better clinical outcomes and less TLR than DES\u2010ISR. ESRD and previous DEB failure were associated to TLR in DES\u2010ISR group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12327","type":"journal-article","created":{"date-parts":[[2016,8,9]],"date-time":"2016-08-09T03:32:33Z","timestamp":1470713553000},"page":"469-479","source":"Crossref","is-referenced-by-count":9,"title":["Comparison of Clinical Results Following the Use of Drug\u2010Eluting Balloons for a Bare\u2010Metal Stent and Drug\u2010Eluting Stent Instent Restenosis"],"prefix":"10.1111","volume":"29","author":[{"given":"Wei\u2010Chieh","family":"Lee","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital Chang Gung University College of Medicine Kaohsiung Taiwan Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yen\u2010Nan","family":"Fang","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang 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