{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T11:03:46Z","timestamp":1774523026474,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,11,4]],"date-time":"2016-11-04T00:00:00Z","timestamp":1478217600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Institute of Health","award":["5K12HL109068-04"],"award-info":[{"award-number":["5K12HL109068-04"]}]},{"name":"National Institute of Health","award":["UL1TR000005"],"award-info":[{"award-number":["UL1TR000005"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the impact of remote ischemic peri\u2010conditioning (RIPC) during inter\u2010facility air medical transport of ST\u2010segment elevation myocardial infarction (STEMI) patients on the incidence of acute kidney injury (AKI) following primary percutaneous coronary intervention (pPCI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>STEMI patients who receive pPCI have an increased risk of AKI for which there is no well\u2010defined prophylactic therapy in the setting of emergent pPCI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using the ACTION Registry\u2010GWTG, we evaluated the impact of RIPC applied during inter\u2010facility helicopter transport of STEMI patients from non\u2010PCI capable hospitals to 2 PCI\u2010hospitals in the United States between March, 2013 and September, 2015 on the incidence of AKI following pPCI. AKI was defined as \u22650.3\u2009mg\/dL increase in creatinine within 48\u201372\u2009hours after pPCI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients who received RIPC (n\u2009=\u2009127), compared to those who did not (n\u2009=\u200992), were less likely to have AKI (11 of 127 patients [8.7%] vs. 17 of 92 patients [18.5%]; adjusted odds ratio\u2009=\u20090.32, 95% CI 0.12\u20130.85, P\u2009=\u20090.023) and all\u2010cause in\u2010hospital mortality (2 of 127 patients [1.6%] vs. 7 of 92 patients [7.6%]; adjusted odds ratio\u2009=\u20090.14, 95% CI 0.02\u20130.86, P\u2009=\u20090.034) after adjusting for socio\u2010demographic and clinical characteristics. There was no difference in hospital length of stay (3 days [interquartile range, 2\u20134] vs. 3 days [interquartile range, 2\u20135], P\u2009=\u20090.357) between the 2 groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>RIPC applied during inter\u2010facility helicopter transport of STEMI patients for pPCI is associated with lower incidence of AKI and in\u2010hospital mortality. The use of RIPC for renal protection in STEMI patients warrants further in depth investigation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12351","type":"journal-article","created":{"date-parts":[[2016,11,4]],"date-time":"2016-11-04T05:19:19Z","timestamp":1478236759000},"page":"603-611","source":"Crossref","is-referenced-by-count":7,"title":["Renal Protection Using Remote Ischemic Peri\u2010Conditioning During Inter\u2010Facility Helicopter Transport of Patients With ST\u2010Segment Elevation Myocardial Infarction: A Retrospective Study"],"prefix":"10.1111","volume":"29","author":[{"given":"Oladipupo","family":"Olafiranye","sequence":"first","affiliation":[{"name":"Division of Cardiology Department of Medicine University of Pittsburgh Pittsburgh Pennsylvania"},{"name":"Department of Emergency Medicine University of Pittsburgh Pittsburgh Pennsylvania"},{"name":"Department of Critical Care Medicine Center for Critical Care Nephrology University of Pittsburgh Pittsburgh 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