{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T00:08:25Z","timestamp":1783210105070,"version":"3.54.6"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T00:00:00Z","timestamp":1479081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the impact of diabetes mellitus (DM) on provisional coronary bifurcation stenting under the complete guidance of intravascular\u2010ultrasound (IVUS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The efficacy of such intervention has not yet been fully elucidated in the DM patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 100 DM and 139 non\u2010DM patients in a prospective multi\u2010center registry of IVUS\u2010guided bifurcation stenting were compared in angiographic results at 9 months. Vessel and luminal changes during the intervention were analyzed using the IVUS. Vascular healing at the follow\u2010up was also investigated in 23 lesions in each group using optical coherence tomography (OCT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No difference was detected regarding baseline reference vessel diameter and minimum lumen diameter in proximal main vessel (MV), distal MV, and side branch (SB). The rate of everolimus\u2010eluting stent use (78.4% vs. 78.3%), final kissing inflation (60.1% vs. 49.0%), and conversion to 2\u2010stent strategy (2.9% vs. 2.8%) were also similar. In the DM group, late loss was greater in proximal MV (DM 0.23\u2009\u00b1\u20090.29 vs. non\u2010DM 0.16\u2009\u00b1\u20090.24\u2009mm, P\u2009&lt;\u20090.05) and SB (0.04\u2009\u00b1\u20090.49 vs. \u22120.08\u2009\u00b1\u20090.35\u2009mm, P\u2009&lt;\u20090.05). Smaller vessel area restricted stent expansion in the proximal MV (6.18\u2009\u00b1\u20091.67 vs. 6.72\u2009\u00b1\u20092.07\u2009mm<jats:sup>2<\/jats:sup>, P\u2009&lt;\u20090.05). More inhomogeneous neointimal coverage (unevenness score, 1.90\u2009\u00b1\u20090.33 vs. 1.72\u2009\u00b1\u20090.29, P\u2009&lt;\u20090.05) and more frequent thrombus attachment (26% vs. 4%, P\u2009&lt;\u20090.05) were documented in the proximal MV at 9\u2010month follow\u2010up OCT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Despite IVUS optimization for coronary bifurcation, DM is potentially associated with smaller luminal gain, higher late\u2010loss, and inhomogeneous vascular healing with frequent thrombus attachment in the proximal MV.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12353","type":"journal-article","created":{"date-parts":[[2016,11,15]],"date-time":"2016-11-15T08:53:29Z","timestamp":1479200009000},"page":"576-587","source":"Crossref","is-referenced-by-count":3,"title":["Impact of Diabetes Mellitus on Intravascular Ultrasound\u2010Guided Provisional Stenting in Coronary Bifurcation Lesions J\u2010REVERSE Sub\u2010Study"],"prefix":"10.1111","volume":"29","author":[{"given":"Masahiro","family":"Yamawaki","sequence":"first","affiliation":[{"name":"Department of Cardiology Saiseikai Yokohama City Eastern Hospital Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Terashita","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kobe University Graduate School of Medicine Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hachidai","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kobe University Graduate School of Medicine Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiro","family":"Shinke","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kobe University Graduate School of Medicine Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichi","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hyogo Medical University Nishinomiya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihisa","family":"Shimada","sequence":"additional","affiliation":[{"name":"Department of Cardiology Shiroyama Hospital Habikino Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Takeda","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rinku General Hospital Izumi\u2010Sano Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichiro","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Cardiology North Harima Medical Center Ono Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihisa","family":"Kinoshita","sequence":"additional","affiliation":[{"name":"Department of Cardiology Toyohashi Heart Center Toyohashi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinobu","family":"Murasato","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kyushu Medical Center Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of J\u2010REVERSE 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