{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:17:51Z","timestamp":1790018271767,"version":"4.0.1"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The purpose of this study is to provide a systematic review of currently available data about the percutaneous trans\u2010coronary\u2010venous mitral annuloplasty with the Carillon Mitral Contour System.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A systematic literature search was conducted using the common medical and scientific databases. The documented parameters included among others grade of mitral regurgitation (MR), vena contracta (VC), effective regurgitant orifice area (EROA), 6 minute\u2010walk\u2010test (6MWT), NYHA\u2010classification, and Quality of Life (QoL) at baseline, 30 days and in the long\u2010term follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The exact total number of successfully implantations with available data remains unclear because so many publications are either of the same institution or study group, or they present overlapping results. Reduction of functional mitral regurgitation (FMR) was associated with significant inverse left\u2010ventricular (LV)) remodeling, improvement in 6MWT, QoL and NYHA\u2010class during the 12\u2010month follow\u2010up. In almost half of the enrolled patients, the Carillon System could not be implanted or had to be removed due to coronary compromission. Adverse advent rate (AE) ranged between 2.8\u201339%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Results with regard to reduction of MR and inverse LV remodeling have been remarkable. Indication and selection criteria for suitable patients, the expected complications, and the long\u2010term results with regard to survival and quality of life still remain unclear. The available results do not establish superiority of the Carillon Mitral Contour System and support the lack of a clear benefit. The approach with the Carillon Mitral Contour System should be limited to participants of prospective and randomized trials.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12370","type":"journal-article","created":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T07:06:49Z","timestamp":1488352009000},"page":"156-162","source":"Crossref","is-referenced-by-count":18,"title":["Treatment of functional mitral regurgitation by percutaneous annuloplasty using the Carillon Mitral Contour System\u2014Currently available data state"],"prefix":"10.1111","volume":"30","author":[{"given":"Dorothee H. L.","family":"Bail","sequence":"first","affiliation":[{"name":"Karl\u2010Olga\u2010Hospital Stuttgart Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.91.4.1022"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezs455"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2014.05.014"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm001"},{"key":"e_1_2_8_6_1","unstructured":"LipieckiJ.Percutaneous Treatment of Functional Mitral Regurgitation: Past Present Carillon\u00ae Results and Future Possibilities\u2014SACIS 10\u201013th April 2014.http:\/\/sacisforum.com\/2014\/wp\u2010content\/uploads\/SACIS\u2010FORUM\u20102014.pdf.2014. 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AHA Scientific Session Chicago November 13\u201017 2010.http:\/\/www.abstractsonline.com\/Plan\/ViewAbstract.aspx?mID\u2009=\u20092552&sKey\u2009=\u200953f16b87\u2010a3f7\u20104062\u20109768\u2010811c28119507&cKey\u2009=\u200988ef1300\u20105d62\u20104384\u20108596\u201074fa35bad836&mKey\u2009=\u2009FAD5CF04\u20107CC9\u2010470A\u20108A02\u2010B69A7E5EA4F3.2010. (Accessed 28th May 2015)."},{"key":"e_1_2_8_11_1","first-page":"Suppl B\u2010TCRT\u201050","article-title":"Subgroup analysis of haemodynamic and clinical response to percutaneous mitral annuloplasty for functional mitral regurgitation in the TITAN trial. 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