{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T13:46:07Z","timestamp":1789911967724,"version":"4.0.1"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,3,21]],"date-time":"2017-03-21T00:00:00Z","timestamp":1490054400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to perform a meta\u2010analysis to compare the outcomes of patients undergoing TAVR with and without balloon post\u2010dilation (PD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>PD is a commonly used technique in TAVR to minimize paravalvular regurgitation (PVR), albeit supported by little evidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Systematic review and meta\u2010analysis of 6 studies comparing 889 patients who had PD compared to 4118 patients without PD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients undergoing PD were more likely male (OR 1.92; 95% CI, 1.41\u20102.61; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and to have coronary artery disease (OR 1.31; 95% CI, 1.03\u20101.68; <jats:italic>P<\/jats:italic>\u2009=\u20090.03) than those patients not requiring PD. There were no significant differences in 30\u2010day mortality (OR 1.24; 95% CI, 0.88\u20101.74; <jats:italic>P<\/jats:italic>\u2009=\u20090.22) and myocardial infarction (OR 0.93; 95% CI, 0.46\u20101.90; <jats:italic>P<\/jats:italic>\u2009=\u20090.85). Patients undergoing TAVR did not have higher 1\u2010year mortality rates (OR 0.98; 95% CI, 0.61\u20101.56; <jats:italic>P<\/jats:italic>\u2009=\u20090.92). The incidence of stroke was significantly greater in patients with PD (OR, 1.71; 95% CI, 1.10\u20102.66). PD was able to reduce the incidence of moderate\u2010severe PVR by 15 fold (OR 15.0; 95% CI, 4.2\u201054.5; <jats:italic>P\u2009<\/jats:italic>&lt;\u20090.001), although rates of moderate\u2010severe PVR were still higher after PD than patients who did not require PD (OR 3.64; 95% CI, 1.96\u20106.75; <jats:italic>P\u2009<\/jats:italic>&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PD significantly improves rates of PVR, however careful patient selection is needed to minimize increased risk of strokes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12378","type":"journal-article","created":{"date-parts":[[2017,3,21]],"date-time":"2017-03-21T14:22:36Z","timestamp":1490106156000},"page":"204-211","source":"Crossref","is-referenced-by-count":36,"title":["Post\u2010dilation in transcatheter aortic valve replacement: A systematic review and 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