{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T09:10:05Z","timestamp":1771233005990,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine whether drug\u2010eluting stent (DES) coronary complete revascularization (CR) confers clinical benefit over incomplete revascularization (IR) in patients with multivessel coronary artery disease (MVD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Clinical benefit of CR over IR in patients with MVD with angina (both stable and unstable) and non\u2010ST\u2010segment elevation myocardial infarction (NSTEMI) in DES has not been well studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a systematic online literature search of PUBMED and EMBASE. Literatures that compared the clinical outcomes between CR and IR with exclusively or majority (&gt;80%) using DES in patients without or included only small portion (&lt;20%) of ST\u2010segment elevation myocardial infarction or single\u2010vessel coronary artery disease were included. Hazards ratio (HR) with 95% confidence interval (CI) was calculated with random\u2010effects model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No randomized clinical trials were identified. A total of 14 observational studies with total of 41\u2009687 patients (CR 39.6% and IR 60.4%) were included in this meta\u2010analysis. CR was associated with lower incident of all\u2010cause mortality (HR 0.71, P\u2009=\u20090.001), major adverse events (HR 0.75, P\u2009&lt;\u20090.001), cardiovascular mortality (HR 0.39, P\u2009&lt;\u20090.001). Meta\u2010regression analysis showed that CR significantly reduced the risk of all\u2010cause mortality in advanced age, triple vessel disease and male sub\u2010groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CR with DES conferred favorable outcomes compared to IR in MVD patients with stable, unstable angina or NTEMI. Further research to achieve higher CR in MVD patients may lead to improvement in prognosis in these cohorts.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12390","type":"journal-article","created":{"date-parts":[[2017,6,2]],"date-time":"2017-06-02T00:52:43Z","timestamp":1496364763000},"page":"309-317","source":"Crossref","is-referenced-by-count":16,"title":["Complete versus incomplete revascularization with drug\u2010eluting stents for multi\u2010vessel disease in stable, unstable angina or non\u2010ST\u2010segment elevation myocardial infarction: A meta\u2010analysis"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6827-8234","authenticated-orcid":false,"given":"Tomo","family":"Ando","sequence":"first","affiliation":[{"name":"Harper Hospital\/Detroit Medical Center, Division of Cardiology Wayne State University Detroit 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