{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T15:49:09Z","timestamp":1762098549694,"version":"3.37.3"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,7,2]],"date-time":"2017-07-02T00:00:00Z","timestamp":1498953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Dr. Gerber's trust charitable research fund"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>We sought to analyze the percutaneous coronary intervention (PCI) outcomes of very elderly patients (V. Eld. group, age &gt;80 years) and compare their outcomes to a less elderly cohort (Eld. group, age 75\u201080 years) traditionally reported in the literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Limited data exist on peri\u2010procedural and long\u2010term outcomes following PCI in the V. Eld. (age &gt;80 years), with under\u2010representation of this cohort in randomized controlled trials. These patients present with advanced complex coronary disease and multiple comorbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All 580 consecutive patients aged \u226575 years (age 80\u2009\u00b1\u20094.9 years, 57.4% males) undergoing PCI between April 2006 and November 2011 were included. A total of 624 consecutive lesions were identified and analyzed. All V. Eld. patients (<jats:italic>n<\/jats:italic>\u2009=\u2009253) were subsequently selected, and their outcomes compared to Eld. patients (<jats:italic>n<\/jats:italic>\u2009=\u2009327). Mean follow\u2010up was 30.8\u2009\u00b1\u20092.7 months with 98% clinical follow\u2010up achieved.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All comparative data are expressed as (V. Eld. vs Eld.) unless otherwise specified. All\u2010cause mortality was significantly higher in the V. Eld. group (11.9% vs 6.1%), although this did not translate into a significant difference in cardiac mortality (6.3% vs 3.7%) or major adverse cardiac and cerebrovascular events (16.2% vs 12.5%). The composite incidence of myocardial infarction (MI), stroke, definite\/probable stent thrombosis, and TIMI major bleed was 4.7%, 1.4% 1.9%, and 6.4%, respectively with no significant difference between both cohorts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study demonstrates an acceptable occurrence of MI, death, repeat intervention, and stent thrombosis in a high\u2010risk group of V. Eld. patients with de novo lesions. Age alone in the absence of other non\u2010cardiac factors should not prohibit a patient from access to PCI.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12400","type":"journal-article","created":{"date-parts":[[2017,7,3]],"date-time":"2017-07-03T04:26:39Z","timestamp":1499055999000},"page":"347-355","source":"Crossref","is-referenced-by-count":14,"title":["Age is not a bar to PCI: Insights from the long\u2010term outcomes from off\u2010site PCI in a real\u2010world setting"],"prefix":"10.1111","volume":"30","author":[{"given":"Robert T.","family":"Gerber","sequence":"first","affiliation":[{"name":"Department of Cardiology Conquest Hospital Hastings East Sussex Healthcare NHS Trust East Sussex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satpal S.","family":"Arri","sequence":"additional","affiliation":[{"name":"Department of Cardiology Conquest Hospital Hastings East Sussex Healthcare NHS Trust East Sussex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9678-5222","authenticated-orcid":false,"given":"Mohamed O.","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Cardiology Conquest Hospital Hastings East Sussex Healthcare NHS Trust East Sussex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gurpreet","family":"Dhillon","sequence":"additional","affiliation":[{"name":"Department of Cardiology Conquest Hospital Hastings East Sussex Healthcare NHS Trust East Sussex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alykhan","family":"Bandali","sequence":"additional","affiliation":[{"name":"Department of Cardiology Conquest Hospital Hastings East Sussex Healthcare NHS Trust East Sussex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Idris","family":"Harding","sequence":"additional","affiliation":[{"name":"Department of Cardiology Conquest Hospital Hastings East Sussex Healthcare NHS Trust East Sussex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Gifford","sequence":"additional","affiliation":[{"name":"Department of Cardiology Conquest Hospital Hastings East Sussex Healthcare NHS Trust East Sussex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Belinda","family":"Sandler","sequence":"additional","affiliation":[{"name":"Department of Cardiology Conquest Hospital Hastings East Sussex Healthcare NHS Trust East Sussex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben","family":"Corbo","sequence":"additional","affiliation":[{"name":"Department of Cardiology Conquest Hospital Hastings East Sussex Healthcare NHS Trust East Sussex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"McWilliams","sequence":"additional","affiliation":[{"name":"Department of Cardiology Conquest Hospital Hastings East Sussex Healthcare NHS Trust East Sussex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,7,2]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"The UK Office of National Statistics. 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