{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T02:49:36Z","timestamp":1775011776421,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,8,30]],"date-time":"2018-08-30T00:00:00Z","timestamp":1535587200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>We report our multicenter experience on continuous hemodynamic monitoring using exclusively the steerable guide catheter (SGC) during MitraClip repair.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Left atrial pressure (LAP) and V\u2010wave are useful to evaluate MitraClip repair but no simple method of continuous monitoring exists.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From 11\/2016 to 8\/2017, 74 patients from four centers with symptomatic moderate\u2010severe to severe mitral regurgitation (MR), underwent MitraClip NT repair with continuous hemodynamic monitoring via the SGC. Real\u2010time LAP\/V\u2010wave changes were compared with transesophageal echocardiography (TEE). When mitral stenosis was suspected, transmitral gradients were verified by invasive hemodynamics. Clinical and echocardiographic outcomes were determined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean age was 78\u2009\u00b1\u200910 years and STS score 9.1\u2009\u00b1\u200911.0%. Pathology included leaflet prolapse\/flail (45%), restriction (35%), and mixed (20%). Number of clips averaged 1.7\u2009\u00b1\u20090.7 per case. There was a significant reduction in LAP (21\u2009\u00b1\u200910 to 15\u2009\u00b1\u20097\u2009mmHg, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) and V\u2010wave(37\u2009\u00b1\u200919 to 24\u2009\u00b1\u200910\u2009mmHg, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) post MitraClip, but the decrease was less in patients with atrial fibrillation (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). Transmitral gradient significantly increased from 2.0\u2009\u00b1\u20091.2 to 4.0\u2009\u00b1\u20091.7\u2009mmHg (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). Paradoxical increases in LAP and V\u2010wave despite MR reduction were observed in three cases requiring MitraClip repositioning or retrieval to avoid stenosis. Follow\u2010up averaged 5.0\u2009\u00b1\u20092.9 months and was 100% complete. KCCQ improvement was significant and MR reduction to <jats:styled-content>&lt;<\/jats:styled-content>1+ was 67% and <jats:styled-content>&lt;<\/jats:styled-content>2+ was 93% at 30 days.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Continuous hemodynamic monitoring using the SGC complements TEE to assess and optimize MitraClip repair in real\u2010time. Further validation is necessary but this feature may be part of future MitraClip and other transcatheter mitral repair systems.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joic.12557","type":"journal-article","created":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T07:27:18Z","timestamp":1535700438000},"page":"907-915","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Continuous invasive hemodynamic monitoring using steerable guide catheter to optimize mitraclip transcatheter mitral valve repair: A multicenter, proof\u2010of\u2010concept study"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7219-990X","authenticated-orcid":false,"given":"Gilbert H. L.","family":"Tang","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery Mount Sinai Health System New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence Y.","family":"Ong","sequence":"additional","affiliation":[{"name":"Department of Cardiology Northwell Health System Bayshore New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Kaple","sequence":"additional","affiliation":[{"name":"Division of Cardiology Westchester Medical Center Valhalla New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basel","family":"Ramlawi","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center Valley Health System Winchester Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanya","family":"Dutta","sequence":"additional","affiliation":[{"name":"Division of Cardiology Westchester Medical Center Valhalla New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed","family":"Zaid","sequence":"additional","affiliation":[{"name":"Division of Cardiology Westchester Medical Center Valhalla New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Division of Cardiology Westchester Medical Center Valhalla New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Kalimi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Northwell Health System Bayshore New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cenap","family":"Undemir","sequence":"additional","affiliation":[{"name":"Section of Cardiothoracic Surgery Westchester Medical Center Valhalla New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asaad","family":"Khan","sequence":"additional","affiliation":[{"name":"Division of Cardiology Mount Sinai Health System New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matias B.","family":"Yudi","sequence":"additional","affiliation":[{"name":"Division of Cardiology Mount Sinai Health System New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Adnan","family":"Nadir","sequence":"additional","affiliation":[{"name":"Division of Cardiology Mount Sinai Health System New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farhan","family":"Majeed","sequence":"additional","affiliation":[{"name":"Division of Cardiology Mount Sinai Health System New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Ali","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center Valley Health System Winchester Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Skiles","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center Valley Health System Winchester Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chandra","family":"Bhim","sequence":"additional","affiliation":[{"name":"Division of Cardiology Mount Sinai Health System New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Cohen","sequence":"additional","affiliation":[{"name":"Division of Cardiology Westchester Medical Center Valhalla New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven L.","family":"Lansman","sequence":"additional","affiliation":[{"name":"Section of Cardiothoracic Surgery Westchester Medical Center Valhalla New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samin K.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Division of Cardiology Mount Sinai Health System New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7189-3307","authenticated-orcid":false,"given":"Annapoorna","family":"Kini","sequence":"additional","affiliation":[{"name":"Division of Cardiology Mount Sinai Health System New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.02.010"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26504"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.116.004856"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.05.053"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27430"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.07.053"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.09.015"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.12.280"},{"key":"e_1_2_10_10_1","first-page":"1052","article-title":"Percutaneous mitral valve interventions in the real word: early and 1\u2010year results from the ACCESS\u2010EU, a prospective, multicenter, non\u2010randomized post\u2010approval study of the MitraClip therapy in Europe","volume":"62","author":"Masiano F","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26868"}],"container-title":["Journal of Interventional Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoic.12557","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joic.12557","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T06:43:42Z","timestamp":1694760222000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joic.12557"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,30]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["10.1111\/joic.12557"],"URL":"https:\/\/doi.org\/10.1111\/joic.12557","archive":["Portico"],"relation":{},"ISSN":["0896-4327","1540-8183"],"issn-type":[{"value":"0896-4327","type":"print"},{"value":"1540-8183","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,30]]},"assertion":[{"value":"2018-05-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}