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Such focal and global hemodynamic biomarkers show the potential of being sensitive to impending cerebrovascular disease and disease progression and can also become useful during planning and follow\u2010up of interventions aiming to restore a normal cerebral circulation.<\/jats:p><jats:p>Here, we describe 4D flow MRI approaches for analyzing the cerebral vasculature. We then survey key hemodynamic biomarkers that can be reliably assessed using the technique. Finally, we highlight cerebrovascular diseases where one or multiple hemodynamic biomarkers are of central interest.<\/jats:p>","DOI":"10.1111\/joim.13392","type":"journal-article","created":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T14:22:04Z","timestamp":1637677324000},"page":"115-127","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["4D flow MRI hemodynamic biomarkers for cerebrovascular diseases"],"prefix":"10.1111","volume":"291","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6784-1945","authenticated-orcid":false,"given":"Anders","family":"W\u00e5hlin","sequence":"first","affiliation":[{"name":"Department of Radiation Sciences Ume\u00e5 University  Ume\u00e5 Sweden"},{"name":"Department of Applied Physics and Electronics Ume\u00e5 University  Ume\u00e5 Sweden"},{"name":"Ume\u00e5 Center for Functional Brain Imaging (UFBI) Ume\u00e5 University  Ume\u00e5 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