{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:36:10Z","timestamp":1792067770430,"version":"4.4.0"},"reference-count":137,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T00:00:00Z","timestamp":1657670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004063","name":"Knut och Alice Wallenbergs Stiftelse","doi-asserted-by":"publisher","award":["KAW 2016.0105"],"award-info":[{"award-number":["KAW 2016.0105"]}],"id":[{"id":"10.13039\/501100004063","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004063","name":"Knut och Alice Wallenbergs Stiftelse","doi-asserted-by":"publisher","award":["KAW 2015.0195"],"award-info":[{"award-number":["KAW 2015.0195"]}],"id":[{"id":"10.13039\/501100004063","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004063","name":"Knut och Alice Wallenbergs Stiftelse","doi-asserted-by":"publisher","award":["KAW 2017.0381"],"award-info":[{"award-number":["KAW 2017.0381"]}],"id":[{"id":"10.13039\/501100004063","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002794","name":"Cancerfonden","doi-asserted-by":"publisher","award":["20\u20101074"],"award-info":[{"award-number":["20\u20101074"]}],"id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Intern Med"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The genetic architecture of cancer has been delineated through advances in high\u2010throughput next\u2010generation sequencing, where the sequential acquisition of recurrent driver mutations initially targeted towards normal cells ultimately leads to malignant transformation. Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are hematologic malignancies frequently initiated by mutations in the normal hematopoietic stem cell compartment leading to the establishment of leukemic stem cells. Although the genetic characterization of MDS and AML has led to identification of new therapeutic targets and development of new promising therapeutic strategies, disease progression, relapse, and treatment\u2010related mortality remain a major challenge in MDS and AML. The selective persistence of rare leukemic stem cells following therapy\u2010induced remission implies unique resistance mechanisms of leukemic stem cells towards conventional therapeutic strategies and that leukemic stem cells represent the cellular origin of relapse. Therefore, targeted surveillance of leukemic stem cells following therapy should, in the future, allow better prediction of relapse and disease progression, but is currently challenged by our restricted ability to distinguish leukemic stem cells from other leukemic cells and residual normal cells. To advance current and new clinical strategies for the treatment of MDS and AML, there is a need to improve our understanding and characterization of MDS and AML stem cells at the cellular, molecular, and genetic levels. Such work has already led to the identification of promising new candidate leukemic stem cell molecular targets that can now be exploited in preclinical and clinical therapeutic strategies, towards more efficient and specific elimination of leukemic stem cells.<\/jats:p>","DOI":"10.1111\/joim.13535","type":"journal-article","created":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T09:13:35Z","timestamp":1657703615000},"page":"262-277","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Targeting stem cells in myelodysplastic syndromes and acute myeloid leukemia"],"prefix":"10.1111","volume":"292","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2340-2526","authenticated-orcid":false,"given":"Petter S.","family":"Woll","sequence":"first","affiliation":[{"name":"Department of Medicine Huddinge Center for Hematology and Regenerative Medicine Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuichi","family":"Yoshizato","sequence":"additional","affiliation":[{"name":"Department of Medicine Huddinge Center for Hematology and Regenerative Medicine Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Hellstr\u00f6m\u2010Lindberg","sequence":"additional","affiliation":[{"name":"Department of Medicine Huddinge Center for Hematology and Regenerative Medicine Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Hematology Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thoas","family":"Fioretos","sequence":"additional","affiliation":[{"name":"Division of Clinical Genetics Department of Laboratory Medicine Lund University  Lund Sweden"},{"name":"Division of Laboratory Medicine Department of Clinical Genetics and Pathology  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin L.","family":"Ebert","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Dana\u2013Farber Cancer Institute  Boston Massachusetts USA"},{"name":"Broad Institute of Harvard and MIT  Cambridge Massachusetts USA"},{"name":"Howard Hughes Medical Institute  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sten Eirik W.","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Department of Medicine Huddinge Center for Hematology and Regenerative Medicine Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Hematology Karolinska University Hospital  Stockholm Sweden"},{"name":"Department of Cell and Molecular Biology Karolinska Institutet  Stockholm Sweden"},{"name":"MRC Molecular Haematology Unit MRC Weatherall Institute of Molecular Medicine University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2017.186"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-022-01717-2"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-020-0290-x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10738"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4409"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2304"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm0797-730"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/367645a0"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-06-2325"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-10-696054"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-10-844696"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1406184"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1516192"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-08-518886"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2013.336"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1301689"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc.2016.112"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2018.01.011"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1408617"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1409405"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-04786-y"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-04312-6"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aay9333"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan4673"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0497-0"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2007.10.001"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1201219"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-01-829937"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-018-0047-7"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0317-6"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13038"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1324297111"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V96.6.2012"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2014.03.036"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1222861110"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-12-399683"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3004315"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0267-4"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2010.12.012"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-10-118331"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2020001742"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2007.01746.x"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2401903"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2009.04.018"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.05.045"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.05.046"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-1659"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404754"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20152008"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1100551108"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2010.11.014"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-01-404699"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-11-679985"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1422749112"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0912228"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1607"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1808777"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1350"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2008.246"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-03-643544"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1904794"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-021-01265-7"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2015.06.012"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198102053040603"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2018.212332"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2020.248955"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12579"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-018-0118-9"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.15.4906"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.24.7999"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(18)30016-4"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2010.06.029"},{"issue":"11","key":"e_1_2_10_74_1","first-page":"1805","article-title":"Intensive chemotherapy for poor prognosis myelodysplasia (MDS) and secondary acute myeloid leukemia (sAML) following MDS of more than 6 months duration. A pilot study by the Leukemia Cooperative Group of the European Organisation for Research and Treatment in Cancer (EORTC\u2010LCG)","volume":"9","author":"Witte T","year":"1995","journal-title":"Leukemia."},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21723"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.04.117"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1605949"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.19.6550"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(09)70003-8"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-08-868752"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.31.8576"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2009.011528"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-1008-z"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-021-00509-w"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2804"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V75.3.555.555"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.70.7091"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.70.7349"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.21.8073"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-04-423046"},{"key":"e_1_2_10_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.06.067"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3742"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.98962"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1804714"},{"key":"e_1_2_10_95_1","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2012.312"},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa061292"},{"key":"e_1_2_10_97_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041668"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature20598"},{"key":"e_1_2_10_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2415"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-019-0230-9"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3930"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-020-0347-5"},{"issue":"6","key":"e_1_2_10_103_1","first-page":"465","article-title":"BiTEs, DARTS, BiKEs and TriKEs\u2014are antibody based therapies changing the future treatment of AML?","volume":"11","author":"Allen C","year":"2021","journal-title":"Life (Basel)."},{"key":"e_1_2_10_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/icb.1996.1"},{"key":"e_1_2_10_105_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1004408107"},{"key":"e_1_2_10_106_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-09-458935"},{"key":"e_1_2_10_107_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.161.10.5614"},{"key":"e_1_2_10_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.03.018"},{"key":"e_1_2_10_109_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02357"},{"key":"e_1_2_10_110_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2017-0604"},{"key":"e_1_2_10_111_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1815105"},{"key":"e_1_2_10_112_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019000173"},{"key":"e_1_2_10_113_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0000000000000691"},{"key":"e_1_2_10_114_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-020-00323-z"},{"key":"e_1_2_10_115_1","doi-asserted-by":"publisher","DOI":"10.1038\/35077225"},{"key":"e_1_2_10_116_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.28.9678"},{"key":"e_1_2_10_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(02)00070-3"},{"key":"e_1_2_10_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(02)00069-7"},{"key":"e_1_2_10_119_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-07-2947"},{"key":"e_1_2_10_120_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-11-057521"},{"key":"e_1_2_10_121_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-12-326843"},{"key":"e_1_2_10_122_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-05-501569"},{"key":"e_1_2_10_123_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08617"},{"key":"e_1_2_10_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2010.01.020"},{"key":"e_1_2_10_125_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1716984"},{"key":"e_1_2_10_126_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-04-779405"},{"key":"e_1_2_10_127_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-022-01556-7"},{"key":"e_1_2_10_128_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V99.12.4638"},{"key":"e_1_2_10_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2014.08.001"},{"key":"e_1_2_10_130_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature14610"},{"key":"e_1_2_10_131_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-019-0109-9"},{"key":"e_1_2_10_132_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-020-0341-y"},{"key":"e_1_2_10_133_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-10-844621"},{"key":"e_1_2_10_134_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4493"},{"key":"e_1_2_10_135_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-021-01328-9"},{"key":"e_1_2_10_136_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V81.5.1369.1369"},{"key":"e_1_2_10_137_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0219547"},{"key":"e_1_2_10_138_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019000519"}],"container-title":["Journal of Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joim.13535","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/joim.13535","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joim.13535","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T21:39:28Z","timestamp":1692826768000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joim.13535"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,13]]},"references-count":137,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1111\/joim.13535"],"URL":"https:\/\/doi.org\/10.1111\/joim.13535","archive":["Portico"],"relation":{},"ISSN":["0954-6820","1365-2796"],"issn-type":[{"value":"0954-6820","type":"print"},{"value":"1365-2796","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,13]]},"assertion":[{"value":"2022-07-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}