{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T04:43:33Z","timestamp":1771562613113,"version":"3.50.1"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T00:00:00Z","timestamp":1418688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>BACKGROUND AND PURPOSE<\/jats:title><jats:p>Whether hemodynamic and\/or embolic transcranial Doppler (TCD) features of internal carotid artery (ICA) stenosis contribute to the classification of stroke patterns on MRI.<\/jats:p><\/jats:sec><jats:sec><jats:title>PATIENTS AND METHODS<\/jats:title><jats:p>Consecutive patients presenting symptomatic \u226550% ICA stenosis were included. Microembolic signals (MES) detection and measurement of cerebral vasoreactivity (VR) were performed by TCD. Only acute MRI lesions, territorial (TT) and\/or borderzone (BZ) were considered.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>A total of 72 ICA stenoses, 27 (38%) moderate (50\u201069%), and 45 (62%) high grade (70\u201099%) were included. MRI lesions showed 32 (44%) pure TT, 20 (28%) pure BZ, and 20 (28%) mixed TT and BZ. Impaired VR was found more frequently among patients with higher degrees of stenoses (<jats:italic>P<\/jats:italic>&lt; .001) whereas MES were similarly encountered in both groups (<jats:italic>P<\/jats:italic>= NS). Impaired VR was more common in the BZ (10\/20, 50%) than in the TT group (9\/32, 28%,<jats:italic>P<\/jats:italic>&lt; .1) while MES were present in 47% (15\/32) of patients with TT and in 30% (6\/20,<jats:italic>P<\/jats:italic>&lt; .1) of those with BZ lesions, in particular in cortical BZ infarcts (<jats:italic>P<\/jats:italic>&lt; .02).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Our findings suggest that TCD characteristics of the ICA stenosis contribute to better define stroke patterns on MRI in about one\u2010third of the patients presenting with pure TT or BZ lesions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jon.12197","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T08:15:41Z","timestamp":1418717741000},"page":"766-775","source":"Crossref","is-referenced-by-count":3,"title":["Embolic and Hemodynamic Transcranial Doppler Characteristics in Patients with Acute Ischemic Stroke due to Carotid Occlusive Disease: Contribution to the Different Infarct Patterns on MRI"],"prefix":"10.1111","volume":"25","author":[{"given":"Hubertus","family":"M\u00fcller","sequence":"first","affiliation":[{"name":"Department of Neurology University Hospitals of Geneva Medical School Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorraine","family":"Fisch","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospitals of Geneva Medical School Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurelien","family":"Viaccoz","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospitals of Geneva Medical School Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Bonvin","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospitals of Geneva Medical School Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl","family":"Lovblad","sequence":"additional","affiliation":[{"name":"Department of Radiology University Hospitals of Geneva Medical School Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vitor","family":"Cuvinciuc","sequence":"additional","affiliation":[{"name":"Department of Radiology University Hospitals of Geneva Medical School Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roman F.","family":"Sztajzel","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospitals of Geneva Medical School Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,12,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.17.1.69"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410060311"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.59.10.1577"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.15.2.221"},{"key":"e_1_2_6_6_1","first-page":"99","article-title":"Watershed infarcts in the brain caused by microemboli","volume":"1","author":"Torvik A","year":"1982","journal-title":"Clin Neuropathol"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.7.1231"},{"key":"e_1_2_6_8_1","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/BF00347803","article-title":"Watershed infarctions and computed tomography. 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