{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T19:49:30Z","timestamp":1779306570180,"version":"3.51.4"},"reference-count":13,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,2,19]],"date-time":"2015-02-19T00:00:00Z","timestamp":1424304000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A 41\u2010year\u2010old male presented with an acute onset of headache, confusion, seizures, and unilateral focal neurological deficit 25 years after receiving whole\u2010brain radiation therapy to treat a cerebellar medulloblastoma. Brain magnetic resonance imaging (MRI) demonstrated a thick unilateral parieto\u2010occipital cortical contrast enhancement. A diagnosis of \u201cStroke\u2010like Migraine Attacks after Radiation Therapy\u201d (SMART) syndrome was made. Here, we describe the brain MR spectroscopy findings of SMART, showing a decrease in N\u2010acetyl\u2010aspartate and increased levels of creatine and choline, corresponding with neuronal destruction or transient neuronal impairment with mild nonspecific gliosis. The absence of a lactate peak suggests that mitochondrial dysfunction, vasospasm or ischemic mechanisms were not involved.<\/jats:p>","DOI":"10.1111\/jon.12227","type":"journal-article","created":{"date-parts":[[2015,2,19]],"date-time":"2015-02-19T13:06:02Z","timestamp":1424351162000},"page":"1056-1058","source":"Crossref","is-referenced-by-count":14,"title":["Brain Magnetic Resonance Spectroscopy Findings in the Stroke\u2010like Migraine Attacks after Radiation Therapy (SMART) Syndrome"],"prefix":"10.1111","volume":"25","author":[{"given":"Emilio","family":"G\u00f3mez\u2010Cibeira","sequence":"first","affiliation":[{"name":"Department of Neurology Hospital Universitario 12 de Octubre  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Calleja\u2010Casta\u00f1o","sequence":"additional","affiliation":[{"name":"Department of Neurology Hospital Universitario 12 de Octubre  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesus","family":"Gonzalez de la Aleja","sequence":"additional","affiliation":[{"name":"Department of Neurology Hospital Universitario 12 de Octubre  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Sierra\u2010Hidalgo","sequence":"additional","affiliation":[{"name":"Department of Neurology Hospital Universitario Infanta Leonor  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Ruiz Morales","sequence":"additional","affiliation":[{"name":"Department of Neurology Hospital Universitario 12 de Octubre  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Salvador\u2010Alvarez","sequence":"additional","affiliation":[{"name":"Department of Neurorradiology Hospital Universitario 12 de Octubre  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Ramos\u2010Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Neurorradiology Hospital Universitario 12 de Octubre  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,19]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2006.01184.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3602"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1215\/15228517-5-2-121"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2001.00285.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2006.12.003"},{"key":"e_1_2_4_7_1","first-page":"833","article-title":"Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome","volume":"23","author":"Eichler FS","year":"2002","journal-title":"Am J Neuroradiol"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2008.02.033"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.22821"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073812474843"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2007.00205.x"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.507020"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A0928"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2008.00306.x"}],"container-title":["Journal of Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjon.12227","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjon.12227","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jon.12227","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T06:33:11Z","timestamp":1696228391000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jon.12227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,19]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.1111\/jon.12227"],"URL":"https:\/\/doi.org\/10.1111\/jon.12227","archive":["Portico"],"relation":{},"ISSN":["1051-2284","1552-6569"],"issn-type":[{"value":"1051-2284","type":"print"},{"value":"1552-6569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,19]]}}}