{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,28]],"date-time":"2024-07-28T05:53:37Z","timestamp":1722146017847},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,4,8]],"date-time":"2016-04-08T00:00:00Z","timestamp":1460073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Isolated central facial palsy (I\u2010CFP) is attributed to a lacunar syndrome affecting the corona radiata region or pons. We examined our acute stroke registry for patients presenting with I\u2010CFP and localized their symptoms to a vascular lesion.<\/jats:p><\/jats:sec><jats:sec><jats:title>SUBJECT &amp; METHODS<\/jats:title><jats:p>Our database of consecutive patients with symptoms of acute cerebral ischemia admitted from January 2008 to December 2012 was reviewed for NIH Stroke Scale (NIHSS) scores and subcomponents. All patients with I\u2010CFP \u00b1 dysarthria (total NIHSS \u2264 3) had contrast\u2010enhanced MR\u2010angiography and transcranial Doppler as standard of care. All ischemic lesions were localized by MRI within 72 hours from symptom onset.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Of 2,202 patients with acute cerebral ischemia, 879 patients (35%) had NIHSS score \u2264 3 points (mean age 63 + 15 years, 46 % women). Nine patients (.4%) presented with I\u2010CFP \u00b1 dysarthria. Of these, only 1 had a lesion in the corona radiata and patent MCA, 1 had a pontine lesion without proximal vessel occlusion (2\/9, or 22%). Remaining 7 patients (78%) had flow\u2010limiting thromboembolic mid\u2010to\u2010distal M1\/proximal M2 MCA disease. Of these, 6 (86%) patients had a prominent early anterior temporal artery on MRA and nonlacunar ischemic lesions on MRI.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Contrary to current teaching of lesion localization for an I\u2010CFP, our study revealed the majority of acute patients presenting with this symptom had evidence of flow\u2010limiting thromboembolic MCA disease rather than a lacunar lesion. Our findings underscore the essential role of comprehensive vascular imaging in patients presenting with I\u2010CFP, which is commonly associated with acute flow\u2010limiting thromboembolic MCA disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jon.12338","type":"journal-article","created":{"date-parts":[[2016,4,10]],"date-time":"2016-04-10T18:00:06Z","timestamp":1460311206000},"page":"499-502","source":"Crossref","is-referenced-by-count":2,"title":["Acute Isolated Central Facial Palsy as Manifestation of Middle Cerebral Artery Ischemia"],"prefix":"10.1111","volume":"26","author":[{"given":"Kara A.","family":"Sands","sequence":"first","affiliation":[{"name":"Comprehensive Stroke Center Department of Neurology, University of Alabama at Birmingham  Birmingham AL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza Bavarsad","family":"Shahripour","sequence":"additional","affiliation":[{"name":"Comprehensive Stroke Center Department of Neurology, University of Alabama at 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