{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T17:21:35Z","timestamp":1792862495871,"version":"4.5.0"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,3,18]],"date-time":"2016-03-18T00:00:00Z","timestamp":1458259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 EB013248, R01 EB018988"],"award-info":[{"award-number":["R01 EB013248, R01 EB018988"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R25 3R25NS070682"],"award-info":[{"award-number":["R25 3R25NS070682"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>PURPOSE<\/jats:title><jats:p>Current diagnosis of fetal posterior fossa anomalies by sonography and conventional MRI is limited by fetal position, motion, and by two\u2010dimensional (2D), rather than three\u2010dimensional (3D), representation.\u00a0In this study, we aimed to validate the use of a novel magnetic resonance imaging (MRI) technique, 3D super\u2010resolution motion\u2010corrected MRI, to image the fetal posterior fossa.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>From a database of pregnant women who received fetal MRIs at our institution, images of\u00a049 normal fetal brains were reconstructed.\u00a0Six measurements of the cerebellum, vermis, and pons were obtained for all cases on 2D conventional and 3D reconstructed MRI, and the agreement between the two methods was determined using concordance correlation coefficients. Concordance of axial and coronal\u00a0measurements of the transcerebellar diameter was also assessed within each method.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Between the two methods, the concordance of measurements was high for all six structures (<jats:italic>P<\/jats:italic> &lt; .001), and was highest for larger structures such as the transcerebellar diameter. Within each method, agreement of axial and coronal measurements of the transcerebellar diameter was superior in 3D reconstructed MRI compared to 2D conventional MRI (<jats:italic>P<\/jats:italic> &lt; .001).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>This comparison study validates the use of 3D super\u2010resolution motion\u2010corrected MRI for imaging the fetal posterior fossa, as this technique results in linear measurements that have high concordance with 2D conventional MRI measurements. Lengths of the transcerebellar diameter measured within a 3D reconstruction are more concordant between imaging planes, as they correct for fetal motion and orthogonal slice acquisition. This technique will facilitate further study of fetal abnormalities of the posterior fossa.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jon.12342","type":"journal-article","created":{"date-parts":[[2016,3,19]],"date-time":"2016-03-19T07:17:38Z","timestamp":1458371858000},"page":"539-544","source":"Crossref","is-referenced-by-count":22,"title":["3D Super\u2010Resolution Motion\u2010Corrected MRI: Validation of Fetal Posterior Fossa Measurements"],"prefix":"10.1111","volume":"26","author":[{"given":"Danielle B.","family":"Pier","sequence":"first","affiliation":[{"name":"Department of Neurology Boston Children's Hospital  Boston MA"},{"name":"Harvard Medical School  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Gholipour","sequence":"additional","affiliation":[{"name":"Department of Radiology Boston Children's Hospital  Boston MA"},{"name":"Computational Radiology Laboratory Boston Children's Hospital  Boston MA"},{"name":"Harvard Medical School  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onur","family":"Afacan","sequence":"additional","affiliation":[{"name":"Department of Radiology Boston Children's Hospital  Boston MA"},{"name":"Computational Radiology Laboratory Boston Children's Hospital  Boston MA"},{"name":"Harvard Medical School  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clemente","family":"Velasco\u2010Annis","sequence":"additional","affiliation":[{"name":"Department of Radiology Boston Children's Hospital  Boston MA"},{"name":"Computational Radiology Laboratory Boston Children's Hospital  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Clancy","sequence":"additional","affiliation":[{"name":"Department of Radiology Boston Children's Hospital  Boston MA"},{"name":"Computational Radiology Laboratory Boston Children's Hospital  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kush","family":"Kapur","sequence":"additional","affiliation":[{"name":"Department of Neurology Boston Children's Hospital  Boston MA"},{"name":"Harvard Medical School  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy A.","family":"Estroff","sequence":"additional","affiliation":[{"name":"Department of Radiology Boston Children's Hospital  Boston MA"},{"name":"Harvard Medical School  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon K.","family":"Warfield","sequence":"additional","affiliation":[{"name":"Department of Radiology Boston Children's Hospital  Boston MA"},{"name":"Computational Radiology Laboratory Boston Children's Hospital  Boston MA"},{"name":"Harvard Medical School  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,3,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20735"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.2004.009"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.10.191"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15782"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-004-1316-3"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.03224.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14900"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15755"},{"key":"e_1_2_6_10_1","first-page":"250","article-title":"Sonographic evaluation of the normal developmental anatomy of the fetal cerebral ventricles: II","volume":"73","author":"Pilu G","year":"1989","journal-title":"The atria. Obstet Gynecol"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.01.128"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4558"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12311-013-0470-2"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2010.2051680"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2006.05.003"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2007.895456"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2009.2030679"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.media.2012.07.004"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-011-0325-x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-012-0418-1"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2015.01.003"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.06.018"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/cmr.a.21321"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.06.054"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2009.04.002"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/RMR.0b013e318267fe94"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7680"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.14.14205"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2007.05.024"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-004-2610-z"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2005.05.004"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6276"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.12.008"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10278-004-1014-6"},{"key":"e_1_2_6_35_1","volume-title":"A language and environment for statistical computing","year":"2013"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0006-341X.2003.00099.x"}],"container-title":["Journal of Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjon.12342","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjon.12342","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jon.12342","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T04:37:11Z","timestamp":1695962231000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jon.12342"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,18]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1111\/jon.12342"],"URL":"https:\/\/doi.org\/10.1111\/jon.12342","archive":["Portico"],"relation":{},"ISSN":["1051-2284","1552-6569"],"issn-type":[{"value":"1051-2284","type":"print"},{"value":"1552-6569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,18]]}}}