{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:31:34Z","timestamp":1787160694579,"version":"build-2736575974"},"reference-count":46,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T00:00:00Z","timestamp":1645660800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T00:00:00Z","timestamp":1645660800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Purpose<\/jats:title>\n                    <jats:p>Angiocentric gliomas (AGs) are epileptogenic low\u2010grade gliomas in young patients. We aimed to investigate the MRI findings of AGs and systematically review previous publications and three new cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We searched PubMed, Elsevier's abstract and citation database, and Embase databases and included 50 patients with pathologically proven AGs with analyzable preoperative MRI including 3 patients from our institution and 47 patients from 38 publications (median age, 13 years [range, 2\u201083 years]; 35 men). Two board\u2010certified radiologists reviewed all images. The relationships between seizure\/epilepsy history and MRI findings were statistically analyzed. Moreover, clinical and imaging differences were evaluated between supratentorial and brainstem AGs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Intratumoral T1\u2010weighted high\u2010intensity areas, stalk\u2010like signs, and regional brain parenchymal atrophy were observed in 23 out of 50 (46.0%), 10 out of 50 (20.0%), and 14 out of 50 (28.0%) patients, respectively. Intratumoral T1\u2010weighted high\u2010intensity areas were observed significantly more frequently in patients with stalk\u2010like signs (positive, 9\/10 vs. negative, 14\/40,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.0031) and regional atrophy (13\/14 vs. 10\/36,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.0001). There were significant relationships between the length of seizure\/epilepsy history and presence of intratumoral T1\u2010weighted high\u2010intensity area (median 3 years vs. 0.5 years,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.0021), stalk\u2010like sign (13.5 vs. 1 year,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.0001), and regional atrophy (14 vs. 0.5 years,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.0001). Patients with brainstem AGs (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a07) did not have a seizure\/epilepsy history and were significantly younger than those with supratentorial AGs (median, 5 vs. 13 years,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.0001, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Intratumoral T1\u2010weighted high\u2010intensity areas, stalk\u2010like signs, and regional brain atrophy were frequent imaging features in AG. We also found that affected age was different between supratentorial and brainstem AGs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jon.12983","type":"journal-article","created":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T11:43:19Z","timestamp":1645702999000},"page":"389-399","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Neuroimaging features of angiocentric glioma: A case series and systematic review"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1186-8900","authenticated-orcid":false,"given":"Ryo","family":"Kurokawa","sequence":"first","affiliation":[{"name":"Division of Neuroradiology, Department of Radiology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Baba","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology, Department of Radiology 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