{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T15:14:31Z","timestamp":1771254871628,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T00:00:00Z","timestamp":1660780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T00:00:00Z","timestamp":1660780800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Purpose<\/jats:title>\n                    <jats:p>The Charlotte Large artery occlusion Endovascular therapy Outcome Score (CLEOS) and Totaled Health Risks in Vascular Events (THRIVE) predict functional outcomes after anterior circulation endovascular thrombectomy (EVT). We evaluated the performance of CLEOS and THRIVE in patients presenting with an acute basilar artery occlusion (BAO) treated with EVT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective analysis of a health system's stroke registry. Patients presenting with an acute BAO treated with EVT and evaluated with pre\u2010thrombectomy CT perfusion (CTP) from January 2017 to December 2021 were included. CLEOS\u00a0=\u00a0(5\u00a0\u00d7\u00a0age)\u00a0+\u00a0(10\u00a0\u00d7\u00a0National Institutes of Health Stroke Scale [NIHSS])\u00a0+\u00a0Glucose\u00a0\u2013\u00a0(150\u00a0\u00d7\u00a0CTP cerebral blood volume index) and THRIVE (0\u20109 points)\u00a0=\u00a0age 60\u201079\u00a0years, 1 point; age\u00a0\u2265\u00a080\u00a0years, 2 points; NIHSS 11\u201020, 2 points; NIHSS\u00a0\u2265\u00a021, 4 points; hypertension, diabetes mellitus, atrial fibrillation, 1 point each. Multivariable logistic regression was performed for the ability of CLEOS and THRIVE to predict the primary outcome, modified Rankin Scale score 3\u20106.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifty\u2010seven patients had mean age 66.6 (\u00b1\u00a014.9) years and median NIHSS 15.5 (5\u201024). In the multivariable regression analysis, increased CLEOS was associated with significantly higher odds of a poor functional outcome (odds ratio [OR]\u00a0=\u00a01.0011, 95% confidence interval [CI]: 1.0003\u20101.0019,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.008), whereas THRIVE was not (OR\u00a0=\u00a01.0326, 95% CI: 0.9478\u20101.1250,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.466). CLEOS\u00a0&gt;\u00a0503 best predicted poor outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A higher CLEOS score was associated with elevated odds of a poor 90\u2010day functional outcome in our cohort of acute BAO patients treated with EVT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jon.13039","type":"journal-article","created":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T22:23:17Z","timestamp":1660861397000},"page":"860-865","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The Charlotte large artery occlusion endovascular therapy outcome score predicts outcome after basilar artery thrombectomy"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2111-5523","authenticated-orcid":false,"given":"Rahul R.","family":"Karamchandani","sequence":"first","affiliation":[{"name":"Department of Neurology Neurosciences Institute, Atrium Health  Charlotte North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sagar","family":"Satyanarayana","sequence":"additional","affiliation":[{"name":"Information and Analytics Services Atrium Health  Charlotte North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongmei","family":"Yang","sequence":"additional","affiliation":[{"name":"Information and Analytics Services Atrium Health  Charlotte North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary","family":"Defilipp","sequence":"additional","affiliation":[{"name":"Charlotte Radiology Neurosciences Institute, Atrium Health  Charlotte North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dale","family":"Strong","sequence":"additional","affiliation":[{"name":"Information and Analytics Services Atrium Health  Charlotte North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy B.","family":"Rhoten","sequence":"additional","affiliation":[{"name":"Department of Neurology Neurosciences Institute, Atrium Health  Charlotte North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikhil M.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Pulmonary and Critical Care Atrium Health  Charlotte North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6697-3724","authenticated-orcid":false,"given":"Andrew W.","family":"Asimos","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Neurosciences Institute, Atrium Health  Charlotte North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2022.106393"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2004.049924"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/15910199221106049"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2014-310250"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2015-012089"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2050"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.002796"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4949.2012.00872.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.1418"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.8.3.383"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.511162"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.001972"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.022606"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.001050"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2014-011351"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4949.2006.00045.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.119.024889"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jon.12889"}],"container-title":["Journal 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