{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T08:32:38Z","timestamp":1783931558600,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Purpose<\/jats:title>\n                    <jats:p>The effectiveness of a large\u2010bore aspiration catheter for contact aspiration (CA) thrombectomy is compared to the combined use of an aspiration catheter and a stent retriever (CA+SR) for large vessel occlusion (LVO). We assessed the efficacy and safety of CA alone versus CA+SR as first\u2010line treatment for middle cerebral artery (MCA) LVO in daily practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed data from the SARA\u20103 registry of patients with MCA occlusion (M1 and M2 segments), dividing them into two groups: first\u2010line CA alone and combined CA+SR. Demographic, clinical, angiographic, and clinical outcomes (National Institute of Health Stroke Scale score at 24\u00a0h and modified Rankin Scale [mRS] score at 3\u00a0months) were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 551 patients, 348 (63.8%) received CA alone and 203 (36.8%) received CA+SR. The groin\u2010to\u2010reperfusion time was significantly shorter in the CA\u2010alone group than in the combined CA+SR group (median, 26 vs. 40\u00a0min,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). The CA group demonstrated higher first\u2010pass modified Thrombolysis In Cerebral Infarction (mTICI) 3 recanalization rates (47%\u00a0vs. 37%; adjusted odds ratio [OR] 1.5 [confidence interval 1\u20132.1],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.042), a higher final mTICI 3 rate (65%\u00a0vs. 56%; OR 1.5 [1\u20132.2],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.037), and fewer new territory embolisms (0.9%\u00a0vs. 3.9%; OR 0.2 [0\u20130.8],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.028) compared to the CA+SR group. The CA\u2010alone group had better functional outcomes at 3\u00a0months (mRS\u00a0\u2264\u00a02, 77%\u00a0vs. 63%; OR 1.9 [1.3\u20133],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.003).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CA alone outperformed CA+SR as a first\u2010line treatment for MCA LVO, yielding higher first\u2010pass and final recanalization rates, lower new territory embolism risk, shorter procedure times, and better functional outcomes at 3\u00a0months.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jon.70065","type":"journal-article","created":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T04:29:07Z","timestamp":1751516947000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Contact Aspiration Alone or Combined With Stent Retriever Thrombectomy for Middle Cerebral Artery Large Vessel Occlusion"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6516-6090","authenticated-orcid":false,"given":"Pedro","family":"Navia","sequence":"first","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology La Paz University Hospital, Hospital La Paz Institute for Health Research\u2010IdiPAZ  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres","family":"Fernandez\u2010Prieto","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology La Paz University Hospital, Hospital La Paz Institute for Health Research\u2010IdiPAZ  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Alvarez\u2010Muelas","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology La Paz University Hospital, Hospital La Paz Institute for Health Research\u2010IdiPAZ  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1ngel","family":"Calleja","sequence":"additional","affiliation":[{"name":"Department of Radiology Hospital Universitario Son Espases  Palma Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquin","family":"Ortega","sequence":"additional","affiliation":[{"name":"Department of Radiology Hospital Universitario Son Espases  Palma Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Interventional Neuroradiology Hospital General Universitario de Alicante  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Sagredo","sequence":"additional","affiliation":[{"name":"Interventional Neuroradiology Hospital General Universitario de Alicante  Valencia 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Stroke Organisation (ESO)\u2014European Society for Minimally Invasive Neurological Therapy (ESMINT) Guidelines on Mechanical Thrombectomy in Acute Ischemic Stroke","volume":"1","author":"Turc G.","year":"2023","journal-title":"Journal of NeuroInterventional Surgery"},{"key":"e_1_2_6_26_1","first-page":"344","article-title":"Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association\/American Stroke Association","volume":"1","author":"Powers W. 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