{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T11:23:26Z","timestamp":1787657006901,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":51,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Purpose<\/jats:title>\n                    <jats:p>Brain magnetic resonance imaging (MRI) is an essential component for outpatient neurological evaluation, though access to timely imaging at the point of care is not feasible for most outpatient neurology practices. Portable ultra\u2010low\u2010field MRI systems offer a potential solution, but studies describing their clinical performance in routine outpatient neurology practice remain limited. This study evaluated clinical concordance and patient experience of portable MRI (pMRI) compared to standard\u2010of\u2010care MRI (sMRI) in independent neurology practices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this prospective, multicenter study, adults presenting to outpatient neurology clinics and requiring clinically indicated brain MRI completed imaging with both pMRI (0.064\u00a0T) and sMRI (91% 3\u00a0T, 9% 1.5\u00a0T) in the neurology clinic. All examinations were independently reviewed by board\u2010certified neuroradiologists in a blinded, randomized fashion without access to clinical history. The primary endpoint was patient\u2010level concordance between modalities for the presence or absence of abnormal findings. Discordant cases underwent post hoc unblinded paired review with clinical history to assess clinical significance. Secondary endpoints included patient\u2010reported experience, assessed using a structured questionnaire evaluating noise, comfort, claustrophobia, anxiety, and overall experience on 10\u2010point Likert scales, as well as modality preference.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 125 participants imaged for common outpatient indications, including headache (40%), cognitive impairment or dementia (16%), multiple sclerosis follow\u2010up (16%), and tumor surveillance (16%), portable and sMRI demonstrated 92% concordance on blinded review. Following clinically informed post hoc review, concordance increased to 98%. pMRI was rated more favorably across all patient experience domains (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001), and participants preferred pMRI (61%) over sMRI (14%) by a 4:1 ratio.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In outpatient neurology practices, pMRI images demonstrated high clinical concordance with sMRI for identifying the presence or absence of structural brain abnormalities and were strongly preferred by patients. These findings support the use of pMRI as a practical point\u2010of\u2010care imaging tool for neurology patients, enabling timely access to structural neuroimaging during the clinical encounter.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jon.70143","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:07:06Z","timestamp":1787314026000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Portable Ultra\u2010Low\u2010Field MRI in Outpatient Neurology: An Examination of Clinical Performance and Patient Experience"],"prefix":"10.1111","volume":"36","author":[{"given":"Laszlo","family":"Mechtler","sequence":"first","affiliation":[{"name":"Dent Neurologic Institute  Buffalo New York USA"},{"name":"Departments of Neurology, Oncology, &amp; Neurosurgery at the Jacobs School of Medicine and Biomedical Sciences State University of New York  Buffalo New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameer Ahmad","family":"Ansari","sequence":"additional","affiliation":[{"name":"Department of Radiology (Interventional Neuroradiology), Neurological Surgery Ken and Ruth Davee Department of Neurology Northwestern University Feinberg School of Medicine  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamal","family":"Derakhshan","sequence":"additional","affiliation":[{"name":"Department of Clinical Radiology University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmond","family":"Knopp","sequence":"additional","affiliation":[{"name":"Hyperfine Inc.  Guilford Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nandor","family":"Pinter","sequence":"additional","affiliation":[{"name":"Dent Neurologic Institute  Buffalo New York USA"},{"name":"Department of Radiology Jacobs School of Medicine and Biomedical Sciences State University of New York  Buffalo New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad Asaad","family":"Nasri","sequence":"additional","affiliation":[{"name":"Texas Neurology  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gincy","family":"Samuel","sequence":"additional","affiliation":[{"name":"Headache Center Texas Neurology  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacr.2023.02.018"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacr.2025.02.031"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacr.2018.09.020"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474\u20104422(17)30470\u20102"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44222\u2010023\u201000086\u2010w"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000210217"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacr.2023.12.028"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.70326"},{"key":"e_1_2_8_10_1","first-page":"17","article-title":"Viewpoints: Why Neuroimaging Plays a Critical Role in Shaping the Future of Neurology","author":"Mechtler L.","year":"2016","journal-title":"Practical Neurology"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41747\u2010025\u201000638\u20102"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.25259\/SNI_162_2024"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000207074"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.28408"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.media.2023.102807"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.add3607"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.26637"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.29002"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.3263"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201025441\u20106"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.26954"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/SVIN.125.002110"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2022.103101"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201054972\u2010x"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.2025.10429"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A7494"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1017\/cjn.2023.250"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjro\/tzaf022"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2024.105515"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2026.07.022"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A8907"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/neo2.70046"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/oso\/9780195326567.001.0001"},{"issue":"2","key":"e_1_2_8_34_1","article-title":"Practical MRI in Neurology: Use Cases, Technologies, and Opportunities for Outpatient Care","volume":"25","author":"Fritz J. 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