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Although MRI currently does not yield sufficient predictive power to provide a diagnosis in most individual cases, important features have been identified in population studies that help support or exclude a clinical diagnosis under consideration. In parkinsonian patients, putamenal signal hypointensity is commonly observed in patients with atypical parkinsonism. In demented patients, hippocampal atrophy and prolonged T2 relaxation may help identify individuals with Alzheimer's disease. 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