{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T22:36:19Z","timestamp":1715553379480},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,2,4]],"date-time":"2016-02-04T00:00:00Z","timestamp":1454544000000},"content-version":"vor","delay-in-days":7339,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[1996,1]]},"abstract":"<jats:p>A variety of disorders affect cerebral hemodynamics. Volume flow rate (VFR) estimates now allow accurate quantification of the effect of cerebrovascular lesions on the conduit vessels, with excellent in vivo and in vitro correlation. Four selected cases with VFR data and angiographic correlation are presented to illustrate potential clinical uses of this method. The VFR estimates were obtained with a color M\u2010mode\u2010based velocity imaging technique, which uses time\u2010domain processing (P\u2010700 Color Velocity Imaging System, Philips Ultrasound International, Irvine, CA). In a patient awaiting coronary artery surgery, with unilateral internal carotid artery occlusion and contralateral angiographic stenosis (50\u201080%, reader variation), the baseline and acetazolamide\u2010challenged common carotid artery VFRs showed excellent conduit function ipsilateral to this stenosis. Thus, the angiographic stenosis did not have significant hemodynamic effects and endarterectomy was avoided. In a patient with an arteriovenous malformation fed by the left vertebral and left external carotid arteries, high in the left cervical region, VFR estimates of two to three times normal predicted the feeding vessels, influenced management, and proved helpful in follow\u2010up. In a patient with subclavian steal syndrome, VFR estimates quantified the steal after brachial hyperemia. Finally, in a patient with delayed vasoconstriction after subarachnoid hemorrhage, very low VFR estimates preceded clinical deterioration. Quantification of hemodynamic changes with VFR estimates was useful for the diagnosis, management, and follow\u2010up of these patients with four types of cerebrovascular disease, and should be applicable in many others.<\/jats:p>","DOI":"10.1111\/jon1996611","type":"journal-article","created":{"date-parts":[[2016,2,8]],"date-time":"2016-02-08T10:32:28Z","timestamp":1454927548000},"page":"1-7","source":"Crossref","is-referenced-by-count":13,"title":["Clinical Cerebrovascular Applications of Arterial Ultrasound Volume Flow Rate Estimates"],"prefix":"10.1111","volume":"6","author":[{"given":"Volker A.","family":"Knappertz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles H.","family":"Tegeler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence G.","family":"Myers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,4]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"S43","article-title":"In-vivo reliability of flow volume measurements with color velocity imaging","volume":"12","author":"Eicke BM","year":"1993","journal-title":"J Ultrasound Med"},{"key":"e_1_2_1_3_1","unstructured":"EickeBM.Flow volume in the carotid artery. 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