{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T04:51:02Z","timestamp":1769230262427,"version":"3.49.0"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,2,4]],"date-time":"2016-02-04T00:00:00Z","timestamp":1454544000000},"content-version":"vor","delay-in-days":7248,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[1996,4]]},"abstract":"<jats:p>American trypanosomiasis (Chagas' disease), a zoonosis caused by Trypanosoma cruzi with a high incidence in Latin America, may induce an uncommon form of localized encephalitis termed \u201cchagoma,\u201d found in few immunocompromised patients. The computed tomography (CT) and magnetic resonance imaging (MRI) findings of brain chagoma are reported for 3 males (ages 32, 32, and 9 yr), the first 2 infected with human immunodeficiency virus (HIV) and the third with acute lymphoblastic leukemia. Diagnosis was confirmed by biopsy. CT disclosed a single, supratentorial, nodular\u2010shaped lesion that substantially enhanced with contrast material, localized in parietal or frontal lobes. T1\u2010weighted MRI showed hypointense lesions that enhanced with gadolinium\u2010diethylenetriaminepentaacetic acid, corresponding to extensive hyperintense areas on T2\u2010weighted images, producing mass effect. The imaging pattern of brain chagoma presented here is similar to that of cerebral toxoplasmosis and should be considered in the differential diagnosis of an intracerebral mass lesion in immunocompromised patients.<\/jats:p>","DOI":"10.1111\/jon19966294","type":"journal-article","created":{"date-parts":[[2016,2,8]],"date-time":"2016-02-08T10:31:50Z","timestamp":1454927510000},"page":"94-97","source":"Crossref","is-referenced-by-count":40,"title":["Chagasic Granulomatous Encephalitis in Immunosuppressed Patients; Computed Tomography and Magnetic Resonance Imaging Findings"],"prefix":"10.1111","volume":"6","author":[{"given":"Guillermo A. Di","family":"Lorenzo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel A","family":"Pagano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana L","family":"Taratuto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria L","family":"Garau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco J","family":"Meli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo D","family":"Pomsztein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,4]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.5.850"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0891-5520(20)30574-2","article-title":"Chagas' disease","volume":"8","author":"Prata A","year":"1994","journal-title":"Infect Dis Clin North Am"},{"key":"e_1_2_1_4_1","first-page":"85","article-title":"American trypanosomiasis (Chagas' disease)","author":"Spina\u2010Fran\u00e7a A","year":"1978","journal-title":"Handbook of clinical neurology, vol 35. 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