{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T04:04:17Z","timestamp":1748837057244,"version":"3.41.0"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,2,4]],"date-time":"2016-02-04T00:00:00Z","timestamp":1454544000000},"content-version":"vor","delay-in-days":6792,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[1997,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study measured the responses of both extracranial (internal carotid arteries) and intracranial (middle cerebral\/angular, basilar arteries) intravascular arterial volume flow rates to acetazolamide using phase\u2010contrast magnetic resonance angiography. Twenty\u2010eight newly studied patients were subdivided into four groups: Group I\u2010Nonocclusive, asymptomatic (n = 7, or 14 carotid and middle cerebral\/angular artery sides); Group II\u2010unilateral carotid transient ischemic attacks, nonhemodynamic (embolic), varying stenoses (n = 11); Group III\u2010unilateral carotid transient ischemic attacks, hemodynamic, varying stenoses (n = 5); and Group IV\u2010unilateral carotid occlusion, asymptomatic (n = 5). The data were separated into nonischemic and ischemic sides so as to illustrate group differences based on vasodilatory responses to acetazolamide. For example, the percent change in volume flow rates over baseline values for the ischemic\u2010side middle cerebral arteries of Group III was significantly the lowest of all of the vasodilatory responses (\u201225 \u00b1 11% vs 40 \u00b1 14% for group II ischemic middle cerebral\/angular artery sides, p = 0.008). Group III patients also had significantly lower standing blood pressures (p = 0.012), higher number of transient ischemic attacks (p = 0.008), and shorter duration of events (p = 0.013). Determinations of volume flow rate continue to assist in determining the degree of hemodynamic compromise of a particular vascular territory.<\/jats:p>","DOI":"10.1111\/jon199773152","type":"journal-article","created":{"date-parts":[[2016,2,8]],"date-time":"2016-02-08T10:30:16Z","timestamp":1454927416000},"page":"152-158","source":"Crossref","is-referenced-by-count":4,"title":["Vasodilatory Responses and Magnetic Resonance Angiography"],"prefix":"10.1111","volume":"7","author":[{"given":"Ross L.","family":"Levine,","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick A.","family":"Turski,","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William D.","family":"Turnipseed,","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas A.","family":"Dulli,","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas M.","family":"Grist,","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,4]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.2.413"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jon199662126"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1961.00450140109011"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.1.1"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jon199663144"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S1064-9689(21)00262-2","article-title":"MR angiography flow analysis. Neurovascular applications","volume":"3","author":"Turski P","year":"1995","journal-title":"Magn Reson Imaging Clin N Am"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jon199663137"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800720506"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.19.8.963"},{"key":"e_1_2_1_11_1","first-page":"138","article-title":"Assessment of cerebral vasoreactivity and stroke risk using XECT acetazolamide challenge","volume":"22","author":"Durham SR","year":"1991","journal-title":"Stroke"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00588426"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.23.2.171"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.1992.20"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1993.79.4.0483"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.6.1193"},{"key":"e_1_2_1_17_1","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S1052-5149(25)00110-8","article-title":"Magnetic resonance angiography and stroke: techniques, applications, and limitations","volume":"2","author":"Crosby DL","year":"1992","journal-title":"Neuroimaging Clin N Am"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.182.2.1732966"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jon199443130"},{"key":"e_1_2_1_20_1","first-page":"197","volume-title":"Progress in stroke research, no. 2","author":"Lassen NA","year":"1983"},{"key":"e_1_2_1_21_1","first-page":"1","article-title":"Tomographic cerebral blood flow measurements in patients with ischemic cerebrovascular disease and evaluation of the vasodilatory capacity by the acetazolamide test","volume":"114","author":"Vostrup S","year":"1988","journal-title":"Acta Neurol Scand Suppl"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI101995"},{"key":"e_1_2_1_23_1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1152\/ajplegacy.1964.206.1.25","article-title":"Arterial pC02 and cerebral hemodynamics","volume":"206","author":"Reivich M","year":"1964","journal-title":"Am J Physiol"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.7.6.584"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.13.2.155"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.19.1.19"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.39.1.25"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.9.1807"},{"key":"e_1_2_1_29_1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1080\/01616412.1981.11739595","article-title":"Cerebral ischemic symptoms in carotid artery occlusion: role of hemodynamic factors","volume":"3","author":"Norving B","year":"1981","journal-title":"Neurol Res"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/106.2.419"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.49.8.899"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1987.66.5.0755"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1988.00520270075023"},{"key":"e_1_2_1_34_1","first-page":"1091","article-title":"Concerning recurrent transient cerebral ischemia attacks","volume":"86","author":"Fisher CM","year":"1962","journal-title":"Can Med J"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.32.12.1379"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410180212"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.16.3.444"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.12.3.353"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)92110-X"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410160504"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-106-1-27"},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.26.1.84"}],"container-title":["Journal of Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjon199773152","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjon199773152","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jon199773152","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T09:55:44Z","timestamp":1748771744000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jon199773152"}},"subtitle":["Extracranial and Intracranial Intravascular Flow Data"],"short-title":[],"issued":{"date-parts":[[1997,7]]},"references-count":41,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,7]]}},"alternative-id":["10.1111\/jon199773152"],"URL":"https:\/\/doi.org\/10.1111\/jon199773152","archive":["Portico"],"relation":{},"ISSN":["1051-2284","1552-6569"],"issn-type":[{"type":"print","value":"1051-2284"},{"type":"electronic","value":"1552-6569"}],"subject":[],"published":{"date-parts":[[1997,7]]}}}