{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T12:34:46Z","timestamp":1759581286074},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,2,4]],"date-time":"2016-02-04T00:00:00Z","timestamp":1454544000000},"content-version":"vor","delay-in-days":6243,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[1999,1]]},"abstract":"<jats:p>Patent ductus arteriosus (PDA) with left\u2010to\u2010right shunting modifies the Doppler flow pattern of the intracranial circulation. The ability of increases in cerebral blood flow velocity (CBFV) to predict shunt resolution during PDA occlusion was evaluated. A 2 MHz transcranial Doppler (TCD) monitored diastolic and mean CBFV, plus the systolidmean CBFV ratio in the middle cerebral artery from before (baseline) to immediately after PDA occlusion. Shunt resolution was verified by echocardiography and\/or angiography. A minimum of 40% increase in diastolic\u2010CBFV from baseline was considered successful resolution. Patients were age\u2010stratified into group I (&lt;15 months; <jats:italic>n<\/jats:italic>=23) and group II (&gt; 15 months; <jats:italic>n<\/jats:italic>=10). Thirty\u2010three children were studied (age, 0.1 to 109 months) during surgical (<jats:italic>n<\/jats:italic>=22) or coil occlusions (<jats:italic>n<\/jats:italic>=11 ). Transcranial Doppler successfully identified shunt resolution in 78% of cases in group I, as compared to 0% in group II (<jats:italic>p<\/jats:italic>&lt;0.01). Identification rate decreased from 79% in cases of minimum ductal diameter of 3 mm (<jats:italic>n<\/jats:italic>=19) to 21% in smaller ductuses (<jats:italic>n<\/jats:italic>=14) (<jats:italic>p<\/jats:italic>&lt;0.01). Body weight and left\u2010atrium size (<jats:italic>p<\/jats:italic>=0.004) in group I and PDA diameter in group II (<jats:italic>p<\/jats:italic>=0.02), were the only preoperative ductal parameters associated with diastolic\u2010CBFV changes after ductus occlusion. Transcranial Doppler detects shunt resolution in infants with moderate to large PDAs.<\/jats:p>","DOI":"10.1111\/jon19999123","type":"journal-article","created":{"date-parts":[[2016,2,8]],"date-time":"2016-02-08T10:09:50Z","timestamp":1454926190000},"page":"23-29","source":"Crossref","is-referenced-by-count":8,"title":["Cerebral Blood Flow Velocity During Occlusive Manipulation of Patent Ductus Arteriosus in Children"],"prefix":"10.1111","volume":"9","author":[{"given":"Rosendo A","family":"Rodriguez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garry","family":"Cornel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin C","family":"Hosking","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nihal","family":"Weerasena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William M","family":"Splinter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimmo","family":"Murto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,4]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/4.4.405"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(81)80408-8"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80658-6"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.58.9.682"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073889004001S11"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80311-9"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410300302"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1983.tb09879.x"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(79)80405-9"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1542\/peds.75.5.887","article-title":"Cerebral blood flow measurement techniques in infants and children","volume":"75","author":"Kirsch JR","year":"1985","journal-title":"Pediatrics"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(83)80502-2"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.48.4.321"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(97)01066-7"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-0770(96)80174-1"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.4.793"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(97)00327-8"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1988.tb10720.x"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/fn.74.1.F63"}],"container-title":["Journal of Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjon19999123","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjon19999123","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jon19999123","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T20:40:56Z","timestamp":1698525656000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jon19999123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1999,1]]}},"alternative-id":["10.1111\/jon19999123"],"URL":"https:\/\/doi.org\/10.1111\/jon19999123","archive":["Portico"],"relation":{},"ISSN":["1051-2284","1552-6569"],"issn-type":[{"value":"1051-2284","type":"print"},{"value":"1552-6569","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,1]]}}}