{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T07:43:06Z","timestamp":1698651786224},"reference-count":9,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,2,4]],"date-time":"2016-02-04T00:00:00Z","timestamp":1454544000000},"content-version":"vor","delay-in-days":5604,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2000,10]]},"abstract":"<jats:p>Harmonic power\u2010based duplex sonography is a new ultrasound method that improves the signal\u2010to\u2010noise ratio of extracranial vascular imaging. The authors evaluated this new method for transtemporal imaging of the basal cerebral arteries. Fundamental power\u2010based duplex sonography (p\u2010TCCS) and harmonic power\u2010based duplex sonography (HI\u2010p\u2010TCCS) in combination with a novel perfluoropropane\u2010containing ultrasound contrast agent (Optison) were investigated for the evaluation of the basal cerebral arteries in 12 healthy volunteers. The number of identified vascular segments and the blood flow velocities in the middle and posterior cerebral arteries were determined for p\u2010TCCS and for two doses of Optison (0.5 and 1.5 mL) using Hl\u2010p\u2010TCCS. Furthermore, the authors determined the time course of signal enhancement after Optison bolus injections. The results were compared using Friedman two\u2010way ANOVA test. Significantly more arterial segments were visualized using Hl\u2010p\u2010TCCS with enhancement of either 0.5 ml or 1.5 ml Optison (p &lt; 0.01, each) than using p\u2010TCCS. The spatial resolution was markedly increased with Hl\u2010p\u2010TCCS, resulting in a striking difference in the detection of distal arterial segments and cortical and parenchymal branches. Except for the diastolic blood flow velocities (BFVs) in the M 1 segment, the BFVs did not differ significantly between p\u2010TCCS and Hl\u2010p\u2010TCCS. Comparing Hl\u2010pTCCS with 0.5 ml and 1.5 ml Optison, the authors found a small but significant reduction of the latency period (18.2 vs. 15.9 seconds, respectively; p &lt; 0.01), a significant increase of the blooming phase (62.7 vs. 99.8 seconds, respectively; p &lt; 0.0006) and a significant prolongation of the diagnostically useful signal enhancement (233.7 vs. 427.6 seconds, respectively; p &lt; 0.004).<\/jats:p>","DOI":"10.1111\/jon2000104216","type":"journal-article","created":{"date-parts":[[2016,2,8]],"date-time":"2016-02-08T10:09:24Z","timestamp":1454926164000},"page":"216-220","source":"Crossref","is-referenced-by-count":1,"title":["Transcranial Harmonic Power Duplex Sonography for the Evaluation of Cerebral Arteries"],"prefix":"10.1111","volume":"10","author":[{"given":"G\u00fcnter","family":"Seidel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnd","family":"Christoph","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Algermissen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Katzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Claasen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion","family":"Vidai\u2010Langwasser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,4]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.26.11.2061"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.192.3.8058946"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1997.tb00225.x"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0301-5629(95)02045-4"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1994.13.5.357"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.26.11.2048"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.28.8.1610"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.9.1901"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0041-624X(96)00033-9"}],"container-title":["Journal of Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjon2000104216","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjon2000104216","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jon2000104216","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T14:27:53Z","timestamp":1698589673000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jon2000104216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,10]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,10]]}},"alternative-id":["10.1111\/jon2000104216"],"URL":"https:\/\/doi.org\/10.1111\/jon2000104216","archive":["Portico"],"relation":{},"ISSN":["1051-2284","1552-6569"],"issn-type":[{"value":"1051-2284","type":"print"},{"value":"1552-6569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,10]]}}}