{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:19:48Z","timestamp":1760955588140},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,2,4]],"date-time":"2016-02-04T00:00:00Z","timestamp":1454544000000},"content-version":"vor","delay-in-days":5604,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2000,10]]},"abstract":"<jats:p>After diagnosing abnormality of cardiac and carotid\u2010cerebral circulation in an infant with isolated ventricular septal defect (VSD) associated with severe congestive heart failure, the authors measured the carotid arterial blood flow volume (CABF). At 3 months, the patient was not thriving and had dyspnea because of severe congestive heart failure. The authors measured the VSD size\/body surface area (BSA) ratio relative to the predicted value of the left ventricular end\u2010diastolic dimension (%LVEDd), left\u2010to\u2010right shunt ratio (Qp\/Qs), and the small stroke volume (SV)\/BSA using echocardiography and cardiac catheterization. The mean, maximum, and minimum CABF (mean CABF, maxCABF, and minCABF) among R\u2010R intervals on electrocardiogram were measured by Doppler flowmetry in this patient and 5 healthy age\u2010matched control children. The patient had a large VSD size\/BSA ratio (37.9 mm\/m<jats:sup>2<\/jats:sup> ), %LVEDd (164%), and Qp\/Qs (3.8), and a small SV\/BSA ratio (18 mUm2 ). The mean CABF, maxCABF, and minCABF were significantly lower than those of control children (VSD patient vs. controls; 2.7 \u00b1 0.4vs. 4.5 \u00b1 0.6, 6.1 \u00b1 0.9 vs. 12.0 \u00b1 2.1, 1.2 \u00b1 0.2 vs. 1.7 \u00b1 0.4 mL sec (mean \u00b1 S.D.)), respectively (<jats:italic>p<\/jats:italic> &lt; 0.01 ). The authors' results showed abnormal cardiac and carotid\u2010cerebral circulation in an infant with large VSD associated with severe congestive heart failure.<\/jats:p>","DOI":"10.1111\/jon2000104241","type":"journal-article","created":{"date-parts":[[2016,2,8]],"date-time":"2016-02-08T10:09:24Z","timestamp":1454926164000},"page":"241-243","source":"Crossref","is-referenced-by-count":2,"title":["Reduction of Carotid Arterial Blood Flow in Ventricular Septal Defect Associated With Severe Congestive Heart Failure"],"prefix":"10.1111","volume":"10","author":[{"given":"Masanobu","family":"Kojo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuhiko","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinnosuke","family":"Akiyoshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miwako","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuro","family":"Izumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,4]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(91)90872-I"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(81)80408-8"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.12.2251"},{"key":"e_1_2_1_5_1","first-page":"241","article-title":"A newly developed noninvasive technique for quantitative measurement of blood flow\u2013with special reference to the measurement of carotid arterial blood flow","volume":"28","author":"Yoshimura S","year":"1981","journal-title":"Jikeikai Med J"},{"key":"e_1_2_1_6_1","first-page":"125","article-title":"Haemodynamic change in carotid blood flow with age","volume":"29","author":"Fujishiro K","year":"1982","journal-title":"Jikeikai Med J"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/13813459309008885"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.14.2.256"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0887-8994(96)80506-6"},{"key":"e_1_2_1_10_1","first-page":"1857","article-title":"Normalization of left ventricular dimension in normal children by two\u2010dimensional echocardiogram","volume":"98","author":"Nagasawa H","year":"1994","journal-title":"J Jpn Pediatr Soc"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.1995.tb03382.x"},{"key":"e_1_2_1_12_1","first-page":"1958","article-title":"The cerebral circulation in the dog with heart failure for experimental left\u2013to\u2013right shunt","volume":"88","author":"Kimura K","year":"1984","journal-title":"J Jpn Pediatr Soc"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(88)80700-5"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.2301\/neurosonology.3.147"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00795640"}],"container-title":["Journal of Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjon2000104241","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjon2000104241","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jon2000104241","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T14:28:44Z","timestamp":1698589724000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jon2000104241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,10]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,10]]}},"alternative-id":["10.1111\/jon2000104241"],"URL":"https:\/\/doi.org\/10.1111\/jon2000104241","archive":["Portico"],"relation":{},"ISSN":["1051-2284","1552-6569"],"issn-type":[{"value":"1051-2284","type":"print"},{"value":"1552-6569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,10]]}}}