{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:19:44Z","timestamp":1791091184567,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,12,27]],"date-time":"2012-12-27T00:00:00Z","timestamp":1356566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Dysphagia is one of the most important complications encountered in amyotrophic lateral sclerosis (<jats:styled-content style=\"fixed-case\">ALS<\/jats:styled-content>). Our aim was to determine whether oropharyngeal dysphagia impacted the quality of life (<jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>o<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>) of patients with <jats:styled-content style=\"fixed-case\">ALS<\/jats:styled-content>. Thirty consecutive patients were recruited (31\u201382\u00a0years, 18 men). Swallowing function was evaluated using a standardised videofluoroscopic barium swallow. All the patients completed a specific questionnaire on quality of life in dysphagia (<jats:styled-content style=\"fixed-case\">SWAL<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>o<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>) immediately after the videofluoroscopy. The results of dysphagia outcome severity scale separated 14 patients with oropharyngeal dysphagia and 16 with normal swallowing function. There was no difference in the average age, weight and body mass index of the two groups (dysphagic patients: 68\u00a0\u00b1\u00a011\u00a0kg versus non\u2010dysphagic patients: 69\u00a0\u00b1\u00a014\u00a0kg). Most of the dysphagic patients had a bulbar affection based on their Norris scores which determine the importance of cranial nerves illness (20\u00a0\u00b1\u00a08), significantly lower than those of the non\u2010dysphagic patients (35\u00a0\u00b1\u00a05) (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b70001). There was no difference in the neurological peripheral symptoms evaluated by Amyotrophic Lateral Sclerosis Functional Rating Scale scores (dysphagic patients: 26\u00a0\u00b1\u00a07 versus non\u2010dysphagic patients: 27\u00a0\u00b1\u00a08) (ns). The swallowing quality of life questionnaire revealed that the dysphagic patients had significant burden (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b7001). They were affected by the necessity to applied a food selection (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b701), by the increase in eating duration (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b705) and described a decrease in eating desire (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b705). They complained of fear regarding the risk of dysphagia (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b705). They also described difficulties with oral communication (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b7001). All of those complained about dysphagia which impacted directly mental health (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b705) and social life (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b705). In conclusion, oropharyngeal dysphagia is a common symptom accompanying <jats:styled-content style=\"fixed-case\">ALS<\/jats:styled-content>, which alters the patient's <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>o<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>, especially social health.<\/jats:p>","DOI":"10.1111\/joor.12019","type":"journal-article","created":{"date-parts":[[2012,12,28]],"date-time":"2012-12-28T02:29:51Z","timestamp":1356661791000},"page":"199-204","source":"Crossref","is-referenced-by-count":63,"title":["Oropharyngeal dysphagia in amyotrophic lateral sclerosis alters quality of life"],"prefix":"10.1111","volume":"40","author":[{"given":"G.","family":"Paris","sequence":"first","affiliation":[{"name":"Department of Physiology Rouen University Hospital Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Martinaud","sequence":"additional","affiliation":[{"name":"Department of Neurology Rouen University Hospital Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Petit","sequence":"additional","affiliation":[{"name":"Department of Nutrition Rouen University Hospital Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Cuvelier","sequence":"additional","affiliation":[{"name":"Department of Pneumology Rouen University Hospital Rouen France"},{"name":"EA 3830 Research Group on Ventilatory Handicaps Rouen University Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Hannequin","sequence":"additional","affiliation":[{"name":"Department of Neurology Rouen University Hospital Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Roppeneck","sequence":"additional","affiliation":[{"name":"CRMPR\u2010HN Les Herbiers Ugecam Group Normandy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Verin","sequence":"additional","affiliation":[{"name":"Department of Physiology Rouen University Hospital Rouen France"},{"name":"EA 3830 Research Group on Ventilatory Handicaps Rouen University Rouen France"},{"name":"CRMPR\u2010HN Les Herbiers Ugecam Group Normandy France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-010-0439-6"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/14660820310016075"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(74)90158-3"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/17482960701374643"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-005-0026-9"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/146608200300079536"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59989770269-9"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00009595"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gcb.2008.12.012"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.24.8.721"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(97)00237-2"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050207"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00417903"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(18)30924-1"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-002-0820-3"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/13548506.2011.651149"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.3109\/17482968.2010.502941"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-011-6191-x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-009-9245-9"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23312"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoor.12019","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoor.12019","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.12019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T16:19:41Z","timestamp":1700669981000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joor.12019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,27]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1111\/joor.12019"],"URL":"https:\/\/doi.org\/10.1111\/joor.12019","archive":["Portico"],"relation":{},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"value":"0305-182X","type":"print"},{"value":"1365-2842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,27]]}}}